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Gene Therapy

Citations 11-20 of 434 total displayed.

Past content (since Aug 1998):

Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells
Thierry VandenDriessche, Zoltán Ivics, Zsuzsanna Izsvák, and Marinee K. L. Chuah
Blood 2009; 114: 1461-1468. [Abstract] [Full text] [PDF]  

Stable gene transfer and expression in cord blood–derived CD34+ hematopoietic stem and progenitor cells by a hyperactive Sleeping Beauty transposon system
Xingkui Xue, Xin Huang, Sonja E. Nodland, Lajos Mátés, Linan Ma, Zsuzsanna Izsvák, Zoltán Ivics, Tucker W. LeBien, R. Scott McIvor, John E. Wagner, and Xianzheng Zhou
Blood 2009; 114: 1319-1330. [Abstract] [Full text] [PDF]  

A novel human gamma-globin gene vector for genetic correction of sickle cell anemia in a humanized sickle mouse model: critical determinants for successful correction
Ajay Perumbeti, Tomoyasu Higashimoto, Fabrizia Urbinati, Robert Franco, Herbert J. Meiselman, David Witte, and Punam Malik
Blood 2009; 114: 1174-1185. [Abstract] [Full text] [PDF]  

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer
Raul Alba, Angela C. Bradshaw, Alan L. Parker, David Bhella, Simon N. Waddington, Stuart A. Nicklin, Nico van Rooijen, Jerome Custers, Jaap Goudsmit, Dan H. Barouch, John H. McVey, and Andrew H. Baker
Blood 2009; 114: 965-971. [Abstract] [Full text] [PDF]  

Correction of murine hemophilia A following nonmyeloablative transplantation of hematopoietic stem cells engineered to encode an enhanced human factor VIII variant using a safety-augmented retroviral vector
Ali Ramezani and Robert G. Hawley
Blood 2009; 114: 526-534. [Abstract] [Full text] [PDF]  

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
Laura A. Johnson, Richard A. Morgan, Mark E. Dudley, Lydie Cassard, James C. Yang, Marybeth S. Hughes, Udai S. Kammula, Richard E. Royal, Richard M. Sherry, John R. Wunderlich, Chyi-Chia R. Lee, Nicholas P. Restifo, Susan L. Schwarz, Alexandria P. Cogdill, Rachel J. Bishop, Hung Kim, Carmen C. Brewer, Susan F. Rudy, Carter VanWaes, Jeremy L. Davis, Aarti Mathur, Robert T. Ripley, Debbie A. Nathan, Carolyn M. Laurencot, and Steven A. Rosenberg
Blood 2009; 114: 535-546. [Abstract] [Full text] [PDF]  

A murine model for induction of long-term immunologic tolerance to factor VIII does not require persistent detectable levels of plasma factor VIII and involves contributions from Foxp3+ T regulatory cells
Hideto Matsui, Masaru Shibata, Brian Brown, Andrea Labelle, Carol Hegadorn, Chandler Andrews, Marinee Chuah, Thierry VandenDriessche, Carol H. Miao, Christine Hough, and David Lillicrap
Blood 2009; 114: 677-685. [Abstract] [Full text] [PDF]  

IL-7 adjuvant treatment enhances long-term tumor antigen-specific CD8+ T-cell responses after immunization with recombinant lentivector
Sara Colombetti, Frédéric Lévy, and Laurence Chapatte
Blood 2009; 113: 6629-6637. [Abstract] [Full text] [PDF]  

Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity
Jorge R. Almeida, Delphine Sauce, David A. Price, Laura Papagno, So Youn Shin, Arnaud Moris, Martin Larsen, Gianfranco Pancino, Daniel C. Douek, Brigitte Autran, Asier Sáez-Cirión, and Victor Appay
Blood 2009; 113: 6351-6360. [Abstract] [Full text] [PDF]  

T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model
Antonio Di Stasi, Biagio De Angelis, Cliona M. Rooney, Lan Zhang, Aruna Mahendravada, Aaron E. Foster, Helen E. Heslop, Malcolm K. Brenner, Gianpietro Dotti, and Barbara Savoldo
Blood 2009; 113: 6392-6402. [Abstract] [Full text] [PDF]  

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