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Gene Therapy

Citations 221-230 of 434 total displayed.

Past content (since Aug 1998):

Defects in T-cell–mediated immunity to influenza virus in murine Wiskott-Aldrich syndrome are corrected by oncoretroviral vector–mediated gene transfer into repopulating hematopoietic cells
Ted S. Strom, Stephen J. Turner, Samita Andreansky, Haiyan Liu, Peter C. Doherty, Deo Kumar Srivastava, John M. Cunningham, and Arthur W. Nienhuis
Blood 2003; 102: 3108-3116. [Abstract] [Full text] [PDF]  

Scaffold attachment region–containing retrovirus vectors improve long-term proviral expression after transplantation of GFP-modified CD34+ baboon repopulating cells
Peter Kurre, Julia Morris, Bobbie Thomasson, Donald B. Kohn, and Hans-Peter Kiem
Blood 2003; 102: 3117-3119. [Abstract] [Full text] [PDF]  

Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/{beta}2-microglobulin–/– repopulating mobilized human peripheral blood CD34+ cells
Sebastian Brenner, Narda L. Whiting-Theobald, Gilda F. Linton, Kevin L. Holmes, Mindy Anderson-Cohen, Patrick F. Kelly, Elio F. Vanin, André M. Pilon, David M. Bodine, Mitchell E. Horwitz, and Harry L. Malech
Blood 2003; 102: 2789-2797. [Abstract] [Full text] [PDF]  

A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopenia
Anja Ehrhardt, Hui Xu, Aaron M. Dillow, Dwight A. Bellinger, Timothy C. Nichols, and Mark A. Kay
Blood 2003; 102: 2403-2411. [Abstract] [Full text] [PDF]  

Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy
Dirk Grimm, Shangzhen Zhou, Hiroyuki Nakai, Clare E. Thomas, Theresa A. Storm, Sally Fuess, Takashi Matsushita, James Allen, Richard Surosky, Michael Lochrie, Leonard Meuse, Alan McClelland, Peter Colosi, and Mark A. Kay
Blood 2003; 102: 2412-2419. [Abstract] [Full text] [PDF]  

A mathematical model of the contribution of endothelial progenitor cells to angiogenesis in tumors: implications for antiangiogenic therapy
Brian R. Stoll, Cristiano Migliorini, Ananth Kadambi, Lance L. Munn, and Rakesh K. Jain
Blood 2003; 102: 2555-2561. [Abstract] [Full text] [PDF]  

Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells
Rosalba Salcedo, Xia Zhang, Howard A. Young, Nelson Michael, Ken Wasserman, Wei-Hong Ma, Manuela Martins-Green, William J. Murphy, and Joost J. Oppenheim
Blood 2003; 102: 1966-1977. [Abstract] [Full text] [PDF]  

Sustained phenotypic correction of canine hemophilia A using an adeno-associated viral vector
Ciaran D. Scallan, David Lillicrap, Haiyan Jiang, Xiaobing Qian, Susannah L. Patarroyo-White, Amy E. Parker, Tongyao Liu, Joseph Vargas, Dea Nagy, Sharon K. Powell, J. Fraser Wright, Patricia V. Turner, Shawn J. Tinlin, Sandra E. Webster, Alan McClelland, and Linda B. Couto
Blood 2003; 102: 2031-2037. [Abstract] [Full text] [PDF]  

Phase 1 trial of FVIII gene transfer for severe hemophilia A using a retroviral construct administered by peripheral intravenous infusion
Jerry S. Powell, Margaret V. Ragni, Gilbert C. White, II, Jeanne M. Lusher, Carol Hillman-Wiseman, Tom E. Moon, Veronica Cole, Sandhya Ramanathan-Girish, Holger Roehl, Nancy Sajjadi, Douglas J. Jolly, and Deborah Hurst
Blood 2003; 102: 2038-2045. [Abstract] [Full text] [PDF]  

Treatment of canine cyclic neutropenia by lentivirus-mediated G-CSF delivery
Ofer Yanay, Simon C. Barry, Louis J. Katen, Margaret Brzezinski, Lisa Y. Flint, Jeffrey Christensen, Denny Liggitt, David C. Dale, and William R. A. Osborne
Blood 2003; 102: 2046-2052. [Abstract] [Full text] [PDF]  

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