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Gene Therapy

Citations 261-270 of 434 total displayed.

Past content (since Aug 1998):

Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells
Stephanie Laufs, Bernhard Gentner, K. Zsuzsanna Nagy, Anna Jauch, Axel Benner, Sonja Naundorf, Klaus Kuehlcke, Bernhard Schiedlmeier, Anthony D. Ho, W. Jens Zeller, and Stefan Fruehauf
Blood 2003; 101: 2191-2198. [Abstract] [Full text] [PDF]  

Retroviral transduction efficiency of G-CSF+SCF-mobilized peripheral blood CD34+ cells is superior to G-CSF or G-CSF+Flt3-L-mobilized cells in nonhuman primates
Peiman Hematti, Stephanie E. Sellers, Brian A. Agricola, Mark E. Metzger, Robert E. Donahue, and Cynthia E. Dunbar
Blood 2003; 101: 2199-2205. [Abstract] [Full text] [PDF]  

Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma
Raphaël F. Rousseau, Ann E. Haight, Charlotte Hirschmann-Jax, Eric S. Yvon, Donna R. Rill, Zhuyong Mei, Susan C. Smith, Shannon Inman, Kristine Cooper, Pat Alcoser, Bambi Grilley, Adrian Gee, Edwina Popek, Andrew Davidoff, Laura C. Bowman, Malcolm K. Brenner, and Douglas Strother
Blood 2003; 101: 1718-1726. [Abstract] [Full text] [PDF]  

Efficient transduction of primary human B lymphocytes and nondividing myeloma B cells with HIV-1-derived lentiviral vectors
Fabrice Bovia, Patrick Salmon, Thomas Matthes, Krisztian Kvell, Tuan H. Nguyen, Christiane Werner-Favre, Marc Barnet, Monika Nagy, Florence Leuba, Jean-François Arrighi, Vincent Piguet, Didier Trono, and Rudolf H. Zubler
Blood 2003; 101: 1727-1733. [Abstract] [Full text] [PDF]  

Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors
Marinee K. L. Chuah, Gudrun Schiedner, Lieven Thorrez, Brian Brown, Marion Johnston, Veerle Gillijns, Sabine Hertel, Nico Van Rooijen, David Lillicrap, Désiré Collen, Thierry VandenDriessche, and Stefan Kochanek
Blood 2003; 101: 1734-1743. [Abstract] [Full text] [PDF]  

High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation
Bernhard Schiedlmeier, Hannes Klump, Elke Will, Gökhan Arman-Kalcek, Zhixiong Li, Zheng Wang, Andreas Rimek, Jutta Friel, Christopher Baum, and Wolfram Ostertag
Blood 2003; 101: 1759-1768. [Abstract] [Full text] [PDF]  

BVL-1-like VL30 promoter sustains long-term expression in erythroid progenitor cells
William R. Staplin and Joseph A. Knezetic
Blood 2003; 101: 1798-1800. [Abstract] [Full text] [PDF]  

Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis
Niels-Bjarne Woods, Arne Muessig, Manfred Schmidt, Johan Flygare, Karin Olsson, Patrick Salmon, Didier Trono, Christof von Kalle, and Stefan Karlsson
Blood 2003; 101: 1284-1289. [Abstract] [Full text] [PDF]  

Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell-depleted stem cell transplantation
Sarah Marktel, Zulma Magnani, Fabio Ciceri, Sabrina Cazzaniga, Stanley R. Riddell, Catia Traversari, Claudio Bordignon, and Chiara Bonini
Blood 2003; 101: 1290-1298. [Abstract] [Full text] [PDF]  

Retroviral-mediated expression of recombinant Fancc enhances the repopulating ability of Fancc-/- hematopoietic stem cells and decreases the risk of clonal evolution
Laura S. Haneline, Xiaxin Li, Samantha L. M. Ciccone, Ping Hong, Yanzhu Yang, Hal E. Broxmeyer, Suk-Hee Lee, Attilio Orazi, Edward F. Srour, and D. Wade Clapp
Blood 2003; 101: 1299-1307. [Abstract] [Full text] [PDF]  

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