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Gene Therapy

Citations 21-30 of 434 total displayed.

Past content (since Aug 1998):

Amelioration of murine β-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both {gamma}-globin and the MGMT drug-resistance gene
Huifen Zhao, Tamara I. Pestina, Md Nasimuzzaman, Perdeep Mehta, Phillip W. Hargrove, and Derek A. Persons
Blood 2009; 113: 5747-5756. [Abstract] [Full text] [PDF]  

Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors
Josette-Renée Landry, Nicolas Bonadies, Sarah Kinston, Kathy Knezevic, Nicola K. Wilson, S. Helen Oram, Mary Janes, Sandie Piltz, Michelle Hammett, Jacinta Carter, Tina Hamilton, Ian J. Donaldson, Georges Lacaud, Jonathan Frampton, George Follows, Valerie Kouskoff, and Berthold Göttgens
Blood 2009; 113: 5783-5792. [Abstract] [Full text] [PDF]  

Toward a stem cell gene therapy for breast cancer
ZongYi Li, Ying Liu, Sebastian Tuve, Ye Xun, Xiaolong Fan, Liang Min, Qinghua Feng, Nancy Kiviat, Hans-Peter Kiem, Mary Leonora Disis, and André Lieber
Blood 2009; 113: 5423-5433. [Abstract] [Full text] [PDF]  

Sustained high-level polyclonal hematopoietic marking and transgene expression 4 years after autologous transplantation of rhesus macaques with SIV lentiviral vector–transduced CD34+ cells
Yoo-Jin Kim, Yoon-Sang Kim, Andre Larochelle, Gabriel Renaud, Tyra G. Wolfsberg, Rima Adler, Robert E. Donahue, Peiman Hematti, Bum-Kee Hong, Jean Roayaei, Keiko Akagi, Janice M. Riberdy, Arthur W. Nienhuis, Cynthia E. Dunbar, and Derek A. Persons
Blood 2009; 113: 5434-5443. [Abstract] [Full text] [PDF]  

Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients
Brian C. Beard, Reeteka Sud, Kirsten A. Keyser, Christina Ironside, Tobias Neff, Sabine Gerull, Grant D. Trobridge, and Hans-Peter Kiem
Blood 2009; 113: 5094-5103. [Abstract] [Full text] [PDF]  

Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection
Robert E. Throm, Annastasia A. Ouma, Sheng Zhou, Anantharaman Chandrasekaran, Timothy Lockey, Michael Greene, Suk See De Ravin, Morvarid Moayeri, Harry L. Malech, Brian P. Sorrentino, and John T. Gray
Blood 2009; 113: 5104-5110. [Abstract] [Full text] [PDF]  

Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells
Michael D. Milsom, Bernhard Schiedlmeier, Jeff Bailey, Mi-Ok Kim, Dandan Li, Michael Jansen, Abdullah Mahmood Ali, Michelle Kirby, Christopher Baum, Leslie J. Fairbairn, and David A. Williams
Blood 2009; 113: 5111-5120. [Abstract] [Full text] [PDF]  

Antineoplastic activity of lentiviral vectors expressing interferon-{alpha} in a preclinical model of primary effusion lymphoma
Maria Luisa Calabrò, Paola Gasperini, Iole Maria Di Gangi, Stefano Indraccolo, Massimo Barbierato, Alberto Amadori, and Luigi Chieco-Bianchi
Blood 2009; 113: 4525-4533. [Abstract] [Full text] [PDF]  

The F12-Vif derivative Chim3 inhibits HIV-1 replication in CD4+ T lymphocytes and CD34+-derived macrophages by blocking HIV-1 DNA integration
Simona Porcellini, Luca Alberici, Francesco Gubinelli, Rossella Lupo, Clelia Olgiati, Gian-Paolo Rizzardi, and Chiara Bovolenta
Blood 2009; 113: 3443-3452. [Abstract] [Full text] [PDF]  

Inhibition of activation-induced death of dendritic cells and enhancement of vaccine efficacy via blockade of MINOR
Tianhong Wang, Qiong Jiang, Camie Chan, Kevin S. Gorski, Erin McCadden, David Kardian, Drew Pardoll, and Katharine A. Whartenby
Blood 2009; 113: 2906-2913. [Abstract] [Full text] [PDF]  

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