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Gene Therapy

Citations 71-80 of 434 total displayed.

Past content (since Aug 1998):

The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies
Catia Traversari, Sarah Marktel, Zulma Magnani, Patrizia Mangia, Vincenzo Russo, Fabio Ciceri, Chiara Bonini, and Claudio Bordignon
Blood 2007; 109: 4708-4715. [Abstract] [Full text] [PDF]  

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance
Brian D. Brown, Giovanni Sitia, Andrea Annoni, Ehud Hauben, Lucia Sergi Sergi, Anna Zingale, Maria Grazia Roncarolo, Luca G. Guidotti, and Luigi Naldini
Blood 2007; 109: 2797-2805. [Abstract] [Full text] [PDF]  

Adenovirus-induced thrombocytopenia: the role of von Willebrand factor and P-selectin in mediating accelerated platelet clearance
Maha Othman, Andrea Labelle, Ian Mazzetti, Hisham S. Elbatarny, and David Lillicrap
Blood 2007; 109: 2832-2839. [Abstract] [Full text] [PDF]  

IRF-4 and c-Rel expression in antiviral-resistant adult T-cell leukemia/lymphoma
Juan Carlos Ramos, Phillip Ruiz, Jr, Lee Ratner, Isildinha M. Reis, Carlos Brites, Celia Pedroso, Gerald E. Byrne, Jr, Ngoc L. Toomey, Valentine Andela, Edward W. Harhaj, Izidore S. Lossos, and William J. Harrington, Jr
Blood 2007; 109: 3060-3068. [Abstract] [Full text] [PDF]  

Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA
Yoko Otake, Sridharan Soundararajan, Tapas K. Sengupta, Ebenezer A. Kio, James C. Smith, Mauricio Pineda-Roman, Robert K. Stuart, Eleanor K. Spicer, and Daniel J. Fernandes
Blood 2007; 109: 3069-3075. [Abstract] [Full text] [PDF]  

Facilitating matched pairing and expression of TCR chains introduced into human T cells
Jürgen Kuball, Michelle L. Dossett, Matthias Wolfl, William Y. Ho, Ralf-Holger Voss, Carla Fowler, and Philip D. Greenberg
Blood 2007; 109: 2331-2338. [Abstract] [Full text] [PDF]  

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates
Amit C. Nathwani, John T. Gray, Jenny McIntosh, Catherine Y. C. Ng, Junfang Zhou, Yunyu Spence, Melanie Cochrane, Elaine Gray, Edward G. D. Tuddenham, and Andrew M. Davidoff
Blood 2007; 109: 1414-1421. [Abstract] [Full text] [PDF]  

Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report
Barbara C. Engel, Greg M. Podsakoff, Joanna L. Ireland, E. Monika Smogorzewska, Denise A. Carbonaro, Kathy Wilson, Ami Shah, Neena Kapoor, Mirna Sweeney, Mark Borchert, Gay M. Crooks, Kenneth I. Weinberg, Robertson Parkman, Howard M. Rosenblatt, Shi-Qi Wu, Michael S. Hershfield, Fabio Candotti, and Donald B. Kohn
Blood 2007; 109: 503-506. [Abstract] [Full text] [PDF]  

Foamy virus–mediated gene transfer to canine repopulating cells
Hans-Peter Kiem, James Allen, Grant Trobridge, Erik Olson, Kirsten Keyser, Laura Peterson, and David W. Russell
Blood 2007; 109: 65-70. [Abstract] [Full text] [PDF]  

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells
Silke Holtkamp, Sebastian Kreiter, Abderraouf Selmi, Petra Simon, Michael Koslowski, Christoph Huber, Özlem Türeci, and Ugur Sahin
Blood 2006; 108: 4009-4017. [Abstract] [Full text] [PDF]  

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