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Oncogenes and Tumor Suppressors

Citations 101-110 of 795 total displayed.

Past content (since May 2000):

CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms
Fenghuang Zhan, Simona Colla, Xiaosong Wu, Bangzheng Chen, James P. Stewart, W. Michael Kuehl, Bart Barlogie, and John D. Shaughnessy, Jr
Blood 2007; 109: 4995-5001. [Abstract] [Full text] [PDF]  

Identification of BCR-ABL point mutations conferring resistance to the Abl kinase inhibitor AMN107 (nilotinib) by a random mutagenesis study
Arghya Ray, Sandra W. Cowan-Jacob, Paul W. Manley, Jürgen Mestan, and James D. Griffin
Blood 2007; 109: 5011-5015. [Abstract] [Full text] [PDF]  

Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase
Francois Guilhot, Jane Apperley, Dong-Wook Kim, Eduardo O. Bullorsky, Michele Baccarani, Gail J. Roboz, Sergio Amadori, Carmino A. de Souza, Jeffrey H. Lipton, Andreas Hochhaus, Dominik Heim, Richard A. Larson, Susan Branford, Martin C. Muller, Prasheen Agarwal, Ashwin Gollerkeri, and Moshe Talpaz
Blood 2007; 109: 4143-4150. [Abstract] [Full text] [PDF]  

The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO
Luke F. Peterson, Ming Yan, and Dong-Er Zhang
Blood 2007; 109: 4392-4398. [Abstract] [Full text] [PDF]  

Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activation
Yun Dai, Payal Khanna, Shuang Chen, Xin-Yan Pei, Paul Dent, and Steven Grant
Blood 2007; 109: 4415-4423. [Abstract] [Full text] [PDF]  

The C/EBP{delta} tumor suppressor is silenced by hypermethylation in acute myeloid leukemia
Shuchi Agrawal, Wolf-Karsten Hofmann, Nicola Tidow, Mathias Ehrich, Dirk van den Boom, Steffen Koschmieder, Wolfgang E. Berdel, Hubert Serve, and Carsten Müller-Tidow
Blood 2007; 109: 3895-3905. [Abstract] [Full text] [PDF]  

Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage
Jennifer A. Cain, Zhifu Xiang, Julie O'Neal, Friederike Kreisel, AnnaLynn Colson, Hui Luo, Lothar Hennighausen, and Michael H. Tomasson
Blood 2007; 109: 3906-3914. [Abstract] [Full text] [PDF]  

Integrated molecular profiling of SOD2 expression in multiple myeloma
Elaine M. Hurt, Suneetha B. Thomas, Benjamin Peng, and William L. Farrar
Blood 2007; 109: 3953-3962. [Abstract] [Full text] [PDF]  

A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy
Anita Boyapati, Ming Yan, Luke F. Peterson, Joseph R. Biggs, Michelle M. Le Beau, and Dong-Er Zhang
Blood 2007; 109: 3963-3971. [Abstract] [Full text] [PDF]  

Pre-TCR expression cooperates with TEL-JAK2 to transform immature thymocytes and induce T-cell leukemia
Nuno R. dos Santos, David S. Rickman, Aurélien de Reynies, Françoise Cormier, Maryvonne Williame, Camille Blanchard, Marc-Henri Stern, and Jacques Ghysdael
Blood 2007; 109: 3972-3981. [Abstract] [Full text] [PDF]  

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