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Oncogenes and Tumor Suppressors

Citations 131-140 of 795 total displayed.

Past content (since May 2000):

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways
Olga S. Kustikova, Hartmut Geiger, Zhixiong Li, Martijn H. Brugman, Stuart M. Chambers, Chad A. Shaw, Karin Pike-Overzet, Dick de Ridder, Frank J. T. Staal, Gottfried von Keudell, Kerstin Cornils, Kalpana Jekumar Nattamai, Ute Modlich, Gerard Wagemaker, Margaret A. Goodell, Boris Fehse, and Christopher Baum
Blood 2007; 109: 1897-1907. [Abstract] [Full text] [PDF]  

4q loss is potentially an important genetic event in MM tumorigenesis: identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3, platelet factor 4
Suk Hang Cheng, Margaret H. L. Ng, Kin Mang Lau, Herman S. Y. Liu, Joyce C. W. Chan, Angela B. Y. Hui, Kwok Wai Lo, Hua Jiang, Jian Hou, Raymond W. Chu, Wai Shan Wong, Natalie P. H. Chan,, and Ho Keung Ng
Blood 2007; 109: 2089-2099. [Abstract] [Full text] [PDF]  

Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR-ABL+ leukemias
Ellen Weisberg, Laurie Catley, Renee D. Wright, Daisy Moreno, Lolita Banerji, Arghya Ray, Paul W. Manley, Juergen Mestan, Doriano Fabbro, Jingrui Jiang, Elizabeth Hall-Meyers, Linda Callahan, Jamie L. DellaGatta, Andrew L. Kung, and James D. Griffin
Blood 2007; 109: 2112-2120. [Abstract] [Full text] [PDF]  

Enhanced natural-killer cell and erythropoietic activities in VEGF-A–overexpressing mice delay F-MuLV–induced erythroleukemia
David Cervi, Yuval Shaked, Mehran Haeri, Tatiana Usenko, Christina R. Lee, Jody J. Haigh, Andras Nagy, Robert S. Kerbel, Eitan Yefenof, and Yaacov Ben-David
Blood 2007; 109: 2139-2146. [Abstract] [Full text] [PDF]  

Adaptive secretion of granulocyte-macrophage colony-stimulating factor (GM-CSF) mediates imatinib and nilotinib resistance in BCR/ABL+ progenitors via JAK-2/STAT-5 pathway activation
Ying Wang, Dali Cai, Cornelia Brendel, Christine Barett, Philipp Erben, Paul W. Manley, Andreas Hochhaus, Andreas Neubauer, and Andreas Burchert
Blood 2007; 109: 2147-2155. [Abstract] [Full text] [PDF]  

Gene-expression profiling of systemic anaplastic large-cell lymphoma reveals differences based on ALK status and two distinct morphologic ALK+ subtypes
Laurence Lamant, Aurélien de Reyniès, Marie-Michèle Duplantier, David S. Rickman, Frédérique Sabourdy, Sylvie Giuriato, Laurence Brugières, Philippe Gaulard, Estelle Espinos, and Georges Delsol
Blood 2007; 109: 2156-2164. [Abstract] [Full text] [PDF]  

Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia
Sebastien Malinge, Raouf Ben-Abdelali, Catherine Settegrana, Isabelle Radford-Weiss, Marianne Debre, Kheira Beldjord, Elizabeth A. Macintyre, Jean-Luc Villeval, William Vainchenker, Roland Berger, Olivier A. Bernard, Eric Delabesse, and Virginie Penard-Lacronique
Blood 2007; 109: 2202-2204. [Abstract] [Full text] [PDF]  

The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas
Yasodha Natkunam, Shuchun Zhao, David Y. Mason, Jun Chen, Behnaz Taidi, Margaret Jones, Anne S. Hammer, Stephen Hamilton Dutoit, Izidore S. Lossos, and Ronald Levy
Blood 2007; 109: 1636-1642. [Abstract] [Full text] [PDF]  

Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways
Obdulio Piloto, Melissa Wright, Patrick Brown, Kyu-Tae Kim, Mark Levis, and Donald Small
Blood 2007; 109: 1643-1652. [Abstract] [Full text] [PDF]  

Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias
Noria Harir, Christian Pecquet, Marc Kerenyi, Karoline Sonneck, Boris Kovacic, Remy Nyga, Marie Brevet, Isabelle Dhennin, Valerie Gouilleux-Gruart, Hartmut Beug, Peter Valent, Kaiss Lassoued, Richard Moriggl, and Fabrice Gouilleux
Blood 2007; 109: 1678-1686. [Abstract] [Full text] [PDF]  

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