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Oncogenes and Tumor Suppressors

Citations 271-280 of 795 total displayed.

Past content (since May 2000):

Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance
Joya Chandra, Jeannette Tracy, David Loegering, Karen Flatten, Srdan Verstovsek, Miloslav Beran, Mercedes Gorre, Zeev Estrov, Nicholas Donato, Moshe Talpaz, Charles Sawyers, Kapil Bhalla, Judith Karp, Edward Sausville, and Scott H. Kaufmann
Blood 2006; 107: 2501-2506. [Abstract] [Full text] [PDF]  

A MAPK/HNRPK pathway controls BCR/ABL oncogenic potential by regulating MYC mRNA translation
Mario Notari, Paolo Neviani, Ramasamy Santhanam, Bradley W. Blaser, Ji-Suk Chang, Annamaria Galietta, Anne E. Willis, Denis C. Roy, Michael A. Caligiuri, Guido Marcucci, and Danilo Perrotti
Blood 2006; 107: 2507-2516. [Abstract] [Full text] [PDF]  

Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial
Deepa Sampath, Jorge Cortes, Zeev Estrov, Min Du, Zheng Shi, Michael Andreeff, Varsha Gandhi, and William Plunkett
Blood 2006; 107: 2517-2524. [Abstract] [Full text] [PDF]  

Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma
Ying-Wei Lin, Rebecca A. Nichols, John J. Letterio, and Peter D. Aplan
Blood 2006; 107: 2540-2543. [Abstract] [Full text] [PDF]  

KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival
Susanne Schnittger, Tobias M. Kohl, Torsten Haferlach, Wolfgang Kern, Wolfgang Hiddemann, Karsten Spiekermann, and Claudia Schoch
Blood 2006; 107: 1791-1799. [Abstract] [Full text] [PDF]  

KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): a study of the Japanese Childhood AML Cooperative Study Group
Akira Shimada, Tomohiko Taki, Ken Tabuchi, Akio Tawa, Keizo Horibe, Masahiro Tsuchida, Ryoji Hanada, Ichiro Tsukimoto, and Yasuhide Hayashi
Blood 2006; 107: 1806-1809. [Abstract] [Full text] [PDF]  

An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor
Judith Staerk, Catherine Lacout, Takeshi Sato, Steven O. Smith, William Vainchenker, and Stefan N. Constantinescu
Blood 2006; 107: 1864-1871. [Abstract] [Full text] [PDF]  

Targeting receptor kinases by a novel indolinone derivative in multiple myeloma: abrogation of stroma-derived interleukin-6 secretion and induction of apoptosis in cytogenetically defined subgroups
Guido Bisping, Martin Kropff, Doris Wenning, Britta Dreyer, Sergey Bessonov, Frank Hilberg, Gerald J. Roth, Gerd Munzert, Martin Stefanic, Matthias Stelljes, Christian Scheffold, Carsten Müller-Tidow, Peter Liebisch, Nicola Lang, Jöelle Tchinda, Hubert L. Serve, Rolf M. Mesters, Wolfgang E. Berdel, and Joachim Kienast
Blood 2006; 107: 2079-2089. [Abstract] [Full text] [PDF]  

FLT3-ITD–, but not BCR/ABL-transformed cells require concurrent Akt/mTor blockage to undergo apoptosis after histone deacetylase inhibitor treatment
Dali Cai, Ying Wang, Oliver G. Ottmann, Peter J. Barth, Andreas Neubauer, and Andreas Burchert
Blood 2006; 107: 2094-2097. [Abstract] [Full text] [PDF]  

V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis
Peter J. Campbell, Martin Griesshammer, Konstanze Döhner, Hartmut Döhner, Rajko Kusec, Hans C. Hasselbalch, Thomas Stauffer Larsen, Niels Pallisgaard, Stéphane Giraudier, Marie-Caroline Le Bousse-Kerdilès, Christophe Desterke, Bernadette Guerton, Brigitte Dupriez, Dominique Bordessoule, Pierre Fenaux, Jean-Jacques Kiladjian, Jean-François Viallard, Jean Brière, Claire N. Harrison, Anthony R. Green, and John T. Reilly
Blood 2006; 107: 2098-2100. [Abstract] [Full text] [PDF]  

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