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Oncogenes and Tumor Suppressors

Citations 301-310 of 795 total displayed.

Past content (since May 2000):

Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9
Hiroyuki Kawagoe and Gerard C. Grosveld
Blood 2005; 106: 4269-4277. [Abstract] [Full text] [PDF]  

MN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in mice
Hiroyuki Kawagoe and Gerard C. Grosveld
Blood 2005; 106: 4278-4286. [Abstract] [Full text] [PDF]  

Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype
Susanne Schnittger, Claudia Schoch, Wolfgang Kern, Cristina Mecucci, Claudia Tschulik, Massimo F. Martelli, Torsten Haferlach, Wolfgang Hiddemann, and Brunangelo Falini
Blood 2005; 106: 3733-3739. [Abstract] [Full text] [PDF]  

Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance
Roel G. W. Verhaak, Chantal S. Goudswaard, Wim van Putten, Maarten A. Bijl, Mathijs A. Sanders, Wendy Hugens, André G. Uitterlinden, Claudia A. J. Erpelinck, Ruud Delwel, Bob Löwenberg, and Peter J. M. Valk
Blood 2005; 106: 3747-3754. [Abstract] [Full text] [PDF]  

Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia
Rosemary E. Gale, Robert Hills, Arnold R. Pizzey, Panagiotis D. Kottaridis, David Swirsky, Amanda F. Gilkes, Elizabeth Nugent, Kenneth I. Mills, Keith Wheatley, Ellen Solomon, Alan K. Burnett, David C. Linch, and David Grimwade, for the NCRI Adult Leukaemia Working Party
Blood 2005; 106: 3768-3776. [Abstract] [Full text] [PDF]  

Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies
Patrick A. Zweidler-McKay, Yiping He, Lanwei Xu, Carlos G. Rodriguez, Fredrick G. Karnell, Andrea C. Carpenter, Jon C. Aster, David Allman, and Warren S. Pear
Blood 2005; 106: 3898-3906. [Abstract] [Full text] [PDF]  

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase
Chiara Ambrogio, Claudia Voena, Andrea D. Manazza, Roberto Piva, Ludovica Riera, Laura Barberis, Carlotta Costa, Guido Tarone, Paola Defilippi, Emilio Hirsch, Elisabetta Boeri Erba, Shabaz Mohammed, Ole N. Jensen, Giorgio Palestro, Giorgio Inghirami, and Roberto Chiarle
Blood 2005; 106: 3907-3916. [Abstract] [Full text] [PDF]  

Constitutive NF-{kappa}B and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival
Lan V. Pham, Archito T. Tamayo, Linda C. Yoshimura, Yen-Chiu Lin-Lee, and Richard J. Ford
Blood 2005; 106: 3940-3947. [Abstract] [Full text] [PDF]  

NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia
Shinya Kimura, Haruna Naito, Hidekazu Segawa, Junya Kuroda, Takeshi Yuasa, Kiyoshi Sato, Asumi Yokota, Yuri Kamitsuji, Eri Kawata, Eishi Ashihara, Yohei Nakaya, Haruna Naruoka, Tatsushi Wakayama, Kimio Nasu, Tetsuo Asaki, Tomoko Niwa, Kazuko Hirabayashi, and Taira Maekawa
Blood 2005; 106: 3948-3954. [Abstract] [Full text] [PDF]  

Extracellular KIT receptor mutants, commonly found in core binding factor AML, are constitutively active and respond to imatinib mesylate
Jörg Cammenga, Stefan Horn, Ulla Bergholz, Gunhild Sommer, Peter Besmer, Walter Fiedler, and Carol Stocking
Blood 2005; 106: 3958-3961. [Abstract] [Full text] [PDF]  

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