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Oncogenes and Tumor Suppressors

Citations 371-380 of 795 total displayed.

Past content (since May 2000):

Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival
Peter S. Hammerman, Casey J. Fox, Morris J. Birnbaum, and Craig B. Thompson
Blood 2005; 105: 4477-4483. [Abstract] [Full text] [PDF]  

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival
Azra J. Alvi, Belinda Austen, Victoria J. Weston, Christopher Fegan, David MacCallum, Athos Gianella-Borradori, David P. Lane, Mike Hubank, Judith E. Powell, Wenbin Wei, A. Malcolm R. Taylor, Paul A. H. Moss, and Tatjana Stankovic
Blood 2005; 105: 4484-4491. [Abstract] [Full text] [PDF]  

Constitutive mobilization of CD34+ cells into the peripheral blood in idiopathic myelofibrosis may be due to the action of a number of proteases
Mingjiang Xu, Edward Bruno, Joseph Chao, Stephen Huang, Guido Finazzi, Steven M. Fruchtman, Uday Popat, Josef T. Prchal, Giovanni Barosi, and Ronald Hoffman, for the MPD Research Consortium
Blood 2005; 105: 4508-4515. [Abstract] [Full text] [PDF]  

AML1-FOG2 fusion protein in myelodysplasia
Edward M. Chan, Elisha M. Comer, Frank C. Brown, Kathleen E. Richkind, Melissa L. Holmes, Beng H. Chong, Roger Shiffman, Dong-Er Zhang, Marilyn L. Slovak, Cheryl L. Willman, Constance T. Noguchi, Yanjun Li, Devan J. Heiber, Lori Kwan, Rebecca J. Chan, Gail H. Vance, Heather C. Ramsey, and Robert A. Hromas
Blood 2005; 105: 4523-4526. [Abstract] [Full text] [PDF]  

Positive and negative regulation of c-Myb by cyclin D1, cyclin-dependent kinases, and p27 Kip1
Wanli Lei, Fan Liu, and Scott A. Ness
Blood 2005; 105: 3855-3861. [Abstract] [Full text] [PDF]  

Activation of Src kinase Lyn by the Kaposi sarcoma–associated herpesvirus K1 protein: implications for lymphomagenesis
Om Prakash, O. Rama Swamy, Xiochang Peng, Zhen-Ya Tang, Li Li, Janet E. Larson, J. Craig Cohen, Javed Gill, Gist Farr, Suizhao Wang, and Felipe Samaniego
Blood 2005; 105: 3987-3994. [Abstract] [Full text] [PDF]  

PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia
Nicholas C. Wolff, Darren R. Veach, William P. Tong, William G. Bornmann, Bayard Clarkson, and Robert L. Ilaria, Jr
Blood 2005; 105: 3995-4003. [Abstract] [Full text] [PDF]  

Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells
Adrián M. Ramos, Carlos Fernández, Donna Amrán, Patricia Sancho, Elena de Blas, and Patricio Aller
Blood 2005; 105: 4013-4020. [Abstract] [Full text] [PDF]  

Synergistic interactions between imatinib mesylate and the novel phosphoinositide-dependent kinase-1 inhibitor OSU-03012 in overcoming imatinib mesylate resistance
Ping-Hui Tseng, Ho-Pi Lin, Jiuxiang Zhu, Kuen-Feng Chen, Erinn M. Hade, Donn C. Young, John C. Byrd, Michael Grever, Kara Johnson, Brian J. Druker, and Ching-Shih Chen
Blood 2005; 105: 4021-4027. [Abstract] [Full text] [PDF]  

Quantitative PCR of bone marrow BCL2/IgH+ cells at diagnosis predicts treatment response and long-term outcome in follicular non-Hodgkin lymphoma
Alessandro Rambaldi, Emanuela Carlotti, Elena Oldani, Irene Della Starza, Michele Baccarani, Sergio Cortelazzo, Francesco Lauria, Luca Arcaini, Enrica Morra, Alessandro Pulsoni, Luigi Rigacci, Maurizio Rupolo, Francesco Zaja, Pier Luigi Zinzani, Tiziano Barbui, and Robert Foa
Blood 2005; 105: 3428-3433. [Abstract] [Full text] [PDF]  

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