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Oncogenes and Tumor Suppressors

Citations 411-420 of 795 total displayed.

Past content (since May 2000):

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation
Joachim Schwäble, Chunaram Choudhary, Christian Thiede, Lara Tickenbrock, Bülent Sargin, Claudia Steur, Maike Rehage, Annika Rudat, Christian Brandts, Wolfgang E. Berdel, Carsten Müller-Tidow, and Hubert Serve
Blood 2005; 105: 2107-2114. [Abstract] [Full text] [PDF]  

Transforming property of TEL-FGFR3 mediated through PI3-K in a T-cell lymphoma that subsequently progressed to AML
Tomoya Maeda, Fumiharu Yagasaki, Maho Ishikawa, Naoki Takahashi, and Masami Bessho
Blood 2005; 105: 2115-2123. [Abstract] [Full text] [PDF]  

Therapy-related acute myeloid leukemia–like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion
Jolanta Libura, Diana J. Slater, Carolyn A. Felix, and Christine Richardson
Blood 2005; 105: 2124-2131. [Abstract] [Full text] [PDF]  

Deregulated expression of the Myc cellular oncogene drives development of mouse "Burkitt-like" lymphomas from naive B cells
Delin Zhu, Chen Feng Qi, Herbert C. Morse, III, Siegfried Janz, and Freda K. Stevenson
Blood 2005; 105: 2135-2137. [Abstract] [Full text] [PDF]  

Tumor metastasis but not tumor growth is dependent on Src-mediated vascular permeability
Michele L. Criscuoli, Mai Nguyen, and Brian P. Eliceiri
Blood 2005; 105: 1508-1514. [Abstract] [Full text] [PDF]  

A cell-based screen for resistance of Bcr-Abl-positive leukemia identifies the mutation pattern for PD166326, an alternative Abl kinase inhibitor
Nikolas von Bubnoff, Darren R. Veach, Heiko van der Kuip, Walter E. Aulitzky, Jana Sänger, Petra Seipel, William G. Bornmann, Christian Peschel, Bayard Clarkson, and Justus Duyster
Blood 2005; 105: 1652-1659. [Abstract] [Full text] [PDF]  

Tissue inhibitor of metalloproteinase 1 (TIMP-1) promotes plasmablastic differentiation of a Burkitt lymphoma cell line: implications in the pathogenesis of plasmacytic/plasmablastic tumors
Liliana Guedez, Antonio Martinez, Shumei Zhao, Angelica Vivero, Stefania Pittaluga, Maryalice Stetler-Stevenson, Mark Raffeld, and William G. Stetler-Stevenson
Blood 2005; 105: 1660-1668. [Abstract] [Full text] [PDF]  

Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species
Jeong H. Kim, Stephanie C. Chu, Jessica L. Gramlich, Yuri B. Pride, Emily Babendreier, Dharminder Chauhan, Ravi Salgia, Klaus Podar, James D. Griffin, and Martin Sattler
Blood 2005; 105: 1717-1723. [Abstract] [Full text] [PDF]  

Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival
Kyu-Tae Kim, Kristin Baird, Joon-Young Ahn, Paul Meltzer, Michael Lilly, Mark Levis, and Donald Small
Blood 2005; 105: 1759-1767. [Abstract] [Full text] [PDF]  

Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3
Prince George, Purva Bali, Srinivas Annavarapu, Anna Scuto, Warren Fiskus, Fei Guo, Celia Sigua, Gautam Sondarva, Lynn Moscinski, Peter Atadja, and Kapil Bhalla
Blood 2005; 105: 1768-1776. [Abstract] [Full text] [PDF]  

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