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Oncogenes and Tumor Suppressors

Citations 431-440 of 795 total displayed.

Past content (since May 2000):

FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression
Patrick Brown, Mark Levis, Sheila Shurtleff, Dario Campana, James Downing, and Donald Small
Blood 2005; 105: 812-820. [Abstract] [Full text] [PDF]  

Inhibition of Akt increases p27Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma
George Z. Rassidakis, Marianna Feretzaki, Coralyn Atwell, Ioannis Grammatikakis, Quan Lin, Raymond Lai, Francois-Xavier Claret, L. Jeffrey Medeiros, and Hesham M. Amin
Blood 2005; 105: 827-829. [Abstract] [Full text] [PDF]  

After chronic myelogenous leukemia: tyrosine kinase inhibitors in other hematologic malignancies
Martha Wadleigh, Daniel J. DeAngelo, James D. Griffin, and Richard M. Stone
Blood 2005; 105: 22-30. [Abstract] [Full text] [PDF]  

Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
Richard M. Stone, Daniel J. DeAngelo, Virginia Klimek, Ilene Galinsky, Eli Estey, Stephen D. Nimer, Wilson Grandin, David Lebwohl, Yanfeng Wang, Pamela Cohen, Edward A. Fox, Donna Neuberg, Jennifer Clark, D. Gary Gilliland, and James D. Griffin
Blood 2005; 105: 54-60. [Abstract] [Full text] [PDF]  

Enforced expression of an Flt3 internal tandem duplication in human CD34+ cells confers properties of self-renewal and enhanced erythropoiesis
Ki Young Chung, Giovanni Morrone, Jan Jacob Schuringa, Bryan Wong, David C. Dorn, and Malcolm A. S. Moore
Blood 2005; 105: 77-84. [Abstract] [Full text] [PDF]  

Dysregulation of granulocyte, erythrocyte, and NK cell lineages in Fli-1 gene–targeted mice
Masahiro Masuya, Omar Moussa, Takanori Abe, Takao Deguchi, Tsukasa Higuchi, Yasuhiro Ebihara, Demetri D. Spyropoulos, Dennis K. Watson, and Makio Ogawa
Blood 2005; 105: 95-102. [Abstract] [Full text] [PDF]  

Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity
Sabine Middendorp, A. J. Esther Zijlstra, Rogier Kersseboom, Gemma M. Dingjan, Hassan Jumaa, and Rudolf W. Hendriks
Blood 2005; 105: 259-265. [Abstract] [Full text] [PDF]  

Physical and functional link of the leukemia-associated factors AML1 and PML
Lan Anh Nguyen, Pier Paolo Pandolfi, Yukiko Aikawa, Yusuke Tagata, Misao Ohki, and Issay Kitabayashi
Blood 2005; 105: 292-300. [Abstract] [Full text] [PDF]  

Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment
Annuska M. Glas, Marie José Kersten, Leonie J. M. J. Delahaye, Anke T. Witteveen, Robby E. Kibbelaar, Arno Velds, Lodewyk F. A. Wessels, Peter Joosten, Ron M. Kerkhoven, René Bernards, Johan H. J. M. van Krieken, Philip M. Kluin, Laura J. van't Veer, and Daphne de Jong
Blood 2005; 105: 301-307. [Abstract] [Full text] [PDF]  

The phosphodiesterase PDE4B limits cAMP-associated PI3K/AKT–dependent apoptosis in diffuse large B-cell lymphoma
Peter G. Smith, Fengfei Wang, Kathryn N. Wilkinson, Kerry J. Savage, Ulf Klein, Donna S. Neuberg, Gideon Bollag, Margaret A. Shipp, and Ricardo C. T. Aguiar
Blood 2005; 105: 308-316. [Abstract] [Full text] [PDF]  

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