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Oncogenes and Tumor Suppressors

Citations 61-70 of 795 total displayed.

Past content (since May 2000):

NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma
Vasiliki Leventaki, Elias Drakos, L. Jeffrey Medeiros, Megan S. Lim, Kojo S. Elenitoba-Johnson, Francois X. Claret, and George Z. Rassidakis
Blood 2007; 110: 1621-1630. [Abstract] [Full text] [PDF]  

Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas
Tint Lwin, Lori A. Hazlehurst, Sophie Dessureault, Raymond Lai, Wenlong Bai, Eduardo Sotomayor, Lynn C. Moscinski, William S. Dalton, and Jianguo Tao
Blood 2007; 110: 1631-1638. [Abstract] [Full text] [PDF]  

JAK2 617V>F–positive polycythemia rubra vera maintained by approximately 18 stochastic stem-cell divisions per year, explaining age of onset by a single rate-limiting mutation
Mark A. Vickers
Blood 2007; 110: 1675-1680. [Abstract] [Full text] [PDF]  

Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel
Ayalew Tefferi, Juergen Thiele, Attilio Orazi, Hans Michael Kvasnicka, Tiziano Barbui, Curtis A. Hanson, Giovanni Barosi, Srdan Verstovsek, Gunnar Birgegard, Ruben Mesa, John T. Reilly, Heinz Gisslinger, Alessandro M. Vannucchi, Francisco Cervantes, Guido Finazzi, Ronald Hoffman, D. Gary Gilliland, Clara D. Bloomfield, and James W. Vardiman
Blood 2007; 110: 1092-1097. [Abstract] [Full text] [PDF]  

In vivo p53 response and immune reaction underlie highly effective low-dose radiotherapy in follicular lymphoma
Laurent Knoops, Rick Haas, Sanne de Kemp, Donné Majoor, Annegien Broeks, Eric Eldering, Jan Paul de Boer, Marcel Verheij, Conny van Ostrom, Annemieke de Vries, Laura van't Veer, and Daphne de Jong
Blood 2007; 110: 1116-1122. [Abstract] [Full text] [PDF]  

Congestive heart failure is a rare event in patients receiving imatinib therapy
Ehab Atallah, Jean-Bernard Durand, Hagop Kantarjian, and Jorge Cortes
Blood 2007; 110: 1233-1237. [Abstract] [Full text] [PDF]  

The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children
Emmanuelle Clappier, Wendy Cuccuini, Anna Kalota, Antoine Crinquette, Jean-Michel Cayuela, Willem A. Dik, Anton W. Langerak, Bertrand Montpellier, Bertrand Nadel, Pierre Walrafen, Olivier Delattre, Alain Aurias, Thierry Leblanc, Hervé Dombret, Alan M. Gewirtz, André Baruchel, François Sigaux, and Jean Soulier
Blood 2007; 110: 1251-1261. [Abstract] [Full text] [PDF]  

FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia
Adam J. Mead, David C. Linch, Robert K. Hills, Keith Wheatley, Alan K. Burnett, and Rosemary E. Gale
Blood 2007; 110: 1262-1270. [Abstract] [Full text] [PDF]  

Gene-expression analysis identifies novel RBL2/p130 target genes in endemic Burkitt lymphoma cell lines and primary tumors
Giulia De Falco, Eleonora Leucci, Dido Lenze, Pier Paolo Piccaluga, Pier Paolo Claudio, Anna Onnis, Giovanna Cerino, Joshua Nyagol, Walter Mwanda, Cristiana Bellan, Michael Hummel, Stefano Pileri, Piero Tosi, Harald Stein, Antonio Giordano, and Lorenzo Leoncini
Blood 2007; 110: 1301-1307. [Abstract] [Full text] [PDF]  

Trisomy 13 is strongly associated with AML1/RUNX1 mutations and increased FLT3 expression in acute myeloid leukemia
Frank Dicker, Claudia Haferlach, Wolfgang Kern, Torsten Haferlach, and Susanne Schnittger
Blood 2007; 110: 1308-1316. [Abstract] [Full text] [PDF]  

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