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Oncogenes and Tumor Suppressors

Citations 71-80 of 795 total displayed.

Past content (since May 2000):

Acute myeloid leukemia with the 8q22;21q22 translocation: secondary mutational events and alternative t(8;21) transcripts
Luke F. Peterson, Anita Boyapati, Eun-Young Ahn, Joseph R. Biggs, Akiko Joo Okumura, Miao-Chia Lo, Ming Yan, and Dong-Er Zhang
Blood 2007; 110: 799-805. [Abstract] [Full text] [PDF]  

Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera or essential thrombocythemia
Alessandro M. Vannucchi, Elisabetta Antonioli, Paola Guglielmelli, Alessandro Rambaldi, Giovanni Barosi, Roberto Marchioli, Rosa Maria Marfisi, Guido Finazzi, Vittoria Guerini, Fabrizio Fabris, Maria Luigia Randi, Valerio De Stefano, Sabrina Caberlon, Agostino Tafuri, Marco Ruggeri, Giorgina Specchia, Vincenzo Liso, Edoardo Rossi, Enrico Pogliani, Luigi Gugliotta, Alberto Bosi, and Tiziano Barbui, for the Italian Group for Malignant Hematologic Disorders of the Adult–Myeloproliferative Disorder Working Party (GIMEMA-MPD WP)
Blood 2007; 110: 840-846. [Abstract] [Full text] [PDF]  

High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2–dependent suppression of C/EBP{alpha}-driven myeloid differentiation
Ji Suk Chang, Ramasamy Santhanam, Rossana Trotta, Paolo Neviani, Anna M. Eiring, Edward Briercheck, Mattia Ronchetti, Denis C. Roy, Bruno Calabretta, Michael A. Caligiuri, and Danilo Perrotti
Blood 2007; 110: 994-1003. [Abstract] [Full text] [PDF]  

The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera
Sabrina Dupont, Aline Massé, Chloé James, Irène Teyssandier, Yann Lécluse, Frédéric Larbret, Valérie Ugo, Patrick Saulnier, Serge Koscielny, Jean Pierre Le Couédic, Nicole Casadevall, William Vainchenker, and François Delhommeau
Blood 2007; 110: 1013-1021. [Abstract] [Full text] [PDF]  

Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia
Michael A. Caligiuri, Roger Briesewitz, Jianhua Yu, Lisheng Wang, Min Wei, Kristy J. Arnoczky, Trent B. Marburger, Jing Wen, Danilo Perrotti, Clara D. Bloomfield, and Susan P. Whitman
Blood 2007; 110: 1022-1024. [Abstract] [Full text] [PDF]  

Increased risk of pregnancy complications in patients with essential thrombocythemia carrying the JAK2 (617V>F) mutation
Francesco Passamonti, Maria Luigia Randi, Elisa Rumi, Ester Pungolino, Chiara Elena, Daniela Pietra, Margherita Scapin, Luca Arcaini, Fabiana Tezza, Remigio Moratti, Cristiana Pascutto, Fabrizio Fabris, Enrica Morra, Mario Cazzola, and Mario Lazzarino
Blood 2007; 110: 485-489. [Abstract] [Full text] [PDF]  

RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells
Hidenori Hattori, Xueqing Zhang, Yonghui Jia, Kulandayan K. Subramanian, Hakryul Jo, Fabien Loison, Peter E. Newburger, and Hongbo R. Luo
Blood 2007; 110: 640-650. [Abstract] [Full text] [PDF]  

Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells
Lori Rink, Artur Slupianek, Tomasz Stoklosa, Margaret Nieborowska-Skorska, Katarzyna Urbanska, Ilona Seferynska, Krzysztof Reiss, and Tomasz Skorski
Blood 2007; 110: 651-660. [Abstract] [Full text] [PDF]  

Prognostic significance of circulating tumor cells in bone marrow or peripheral blood as detected by qualitative and quantitative PCR in pediatric NPM-ALK–positive anaplastic large-cell lymphoma
Christine Damm-Welk, Kerstin Busch, Birgit Burkhardt, Jutta Schieferstein, Susanne Viehmann, Ilske Oschlies, Wolfram Klapper, Martin Zimmermann, Jochen Harbott, Alfred Reiter, and Willi Woessmann
Blood 2007; 110: 670-677. [Abstract] [Full text] [PDF]  

Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I–induced leukemia and suppresses leukemic stem cells
Cong Peng, Julia Brain, Yiguo Hu, Ami Goodrich, Linghong Kong, David Grayzel, Roger Pak, Margaret Read, and Shaoguang Li
Blood 2007; 110: 678-685. [Abstract] [Full text] [PDF]  

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