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Oncogenes and Tumor Suppressors

Citations 81-90 of 795 total displayed.

Past content (since May 2000):

Arginine 595 is duplicated in patients with acute leukemias carrying internal tandem duplications of FLT3 and modulates its transforming potential
Sridhar Vempati, Carola Reindl, Seshu Kumar Kaza, Ruth Kern, Theodora Malamoussi, Martin Dugas, Gudrun Mellert, Susanne Schnittger, Wolfgang Hiddemann, and Karsten Spiekermann
Blood 2007; 110: 686-694. [Abstract] [Full text] [PDF]  

Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders
John M. Joslin, Anthony A. Fernald, Thelma R. Tennant, Elizabeth M. Davis, Scott C. Kogan, John Anastasi, John D. Crispino, and Michelle M. Le Beau
Blood 2007; 110: 719-726. [Abstract] [Full text] [PDF]  

Kinase domain mutations of BCR-ABL frequently precede imatinib-based therapy and give rise to relapse in patients with de novo Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL)
Heike Pfeifer, Barbara Wassmann, Anna Pavlova, Lydia Wunderle, Johannes Oldenburg, Anja Binckebanck, Thoralf Lange, Andreas Hochhaus, Silvia Wystub, Patrick Brück, Dieter Hoelzer, and Oliver G. Ottmann
Blood 2007; 110: 727-734. [Abstract] [Full text] [PDF]  

NF-{kappa}B2 mutation targets TRAF1 to induce lymphomagenesis
Baochun Zhang, Zhe Wang, Tai Li, Erdyni N. Tsitsikov, and Han-Fei Ding
Blood 2007; 110: 743-751. [Abstract] [Full text] [PDF]  

High PR3 or ELA2 expression by CD34+ cells in advanced-phase chronic myeloid leukemia is associated with improved outcome following allogeneic stem cell transplantation and may improve PR1 peptide–driven graft-versus-leukemia effects
Agnes S. M. Yong, Katayoun Rezvani, Bipin N. Savani, Rhoda Eniafe, Stephan Mielke, John M. Goldman, and A. John Barrett
Blood 2007; 110: 770-775. [Abstract] [Full text] [PDF]  

Ubp43 regulates BCR-ABL leukemogenesis via the type 1 interferon receptor signaling
Ming Yan, Jiann-Kae Luo, Kenneth J. Ritchie, Ikuya Sakai, Kasuto Takeuchi, Ruibao Ren, and Dong-Er Zhang
Blood 2007; 110: 305-312. [Abstract] [Full text] [PDF]  

Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance
Jennifer S. Carew, Steffan T. Nawrocki, Charissa N. Kahue, Hui Zhang, Chunying Yang, Linda Chung, Janet A. Houghton, Peng Huang, Francis J. Giles, and John L. Cleveland
Blood 2007; 110: 313-322. [Abstract] [Full text] [PDF]  

A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia
Ting-lei Gu, Thomas Mercher, Jeffrey W. Tyner, Valerie L. Goss, Denise K. Walters, Melanie G. Cornejo, Cynthia Reeves, Lana Popova, Kimberly Lee, Michael C. Heinrich, John Rush, Masanori Daibata, Isao Miyoshi, D. Gary Gilliland, Brian J. Druker, and Roberto D. Polakiewicz
Blood 2007; 110: 323-333. [Abstract] [Full text] [PDF]  

Different STAT-3 and STAT-5 phosphorylation discriminates among Ph-negative chronic myeloproliferative diseases and is independent of the V617F JAK-2 mutation
Luciana Teofili, Maurizio Martini, Tonia Cenci, Giovanna Petrucci, Lorenza Torti, Sergio Storti, Francesco Guidi, Giuseppe Leone, and Luigi Maria Larocca
Blood 2007; 110: 354-359. [Abstract] [Full text] [PDF]  

Activation mechanisms of STAT5 by oncogenic Flt3-ITD
Chunaram Choudhary, Christian Brandts, Joachim Schwable, Lara Tickenbrock, Bülent Sargin, Andrea Ueker, Frank-D. Böhmer, Wolfgang E. Berdel, Carsten Müller-Tidow, and Hubert Serve
Blood 2007; 110: 370-374. [Abstract] [Full text] [PDF]  

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