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Blood, 1946, Vol. 1, No. 2, pp. 121-128.
© 1946 American Society of Hematology, Inc.

THE CARDIOVASCULAR SYSTEM IN ANEMIA

WITH A NOTE ON THE PARTICULAR ABNORMALITIES IN SICKLE CELL ANEMIA

MAXWELL M. WINTROBE M.D.1

1 Department of Medicine, University of Utah, Salt Lake City; read before the Fifteenth Annual Graduate Symposium on Heart Disease, Heart Committee of the San Francisco Tuberculosis Association, San Francisco, Oct. 26, 1944.

The symptoms and signs referable to the cardiovascular system that are associated with anemia are discussed, and the physiologic adjustments to anemia that take place in the cardiovascular system are considered. The capacity for adjustment when anemia develops gradually, appears to be very great. The remarkable changes found in the cardiovascular system in cases of sickle cell anemia may be the result of adjustments to severe anemia of exceptional chronicity.


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