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Blood, 1946, Vol. 1, No. 2, pp. 143-155.
© 1946 American Society of Hematology, Inc.


ERYTHROBLASTOSIS FETALIS IN THE FIRST-BORN

PREVENTION OF ITS MOST SEVERE FORMS

PHILIP LEVINE M.D.1 and R. K. WALLER M.D.1

1 Laboratories of the Ortho Research Foundation, Linden, N.J.

The incidence of fatal forms of erythroblastosis fetalis in the first-born can be diminished by the simple measure of transfusing all Rh negative female patients, even as infants, with Rh negative blood. Once a female patient is found to be Rh negative, all subsequent transfusions must be carried out with Rh negative blood. The indications are that sufficient human anti-Rh serums will become available for the more extensive Rh tests required for the prevention of iso-immunization by transfusion.


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