Blood, 1946, Vol. 1, No. 2, pp. 143-155.
© 1946 American Society of Hematology, Inc.
ERYTHROBLASTOSIS FETALIS IN THE FIRST-BORN
PREVENTION OF ITS MOST SEVERE FORMS
PHILIP LEVINE M.D.1 and
R. K. WALLER M.D.1
1 Laboratories of the Ortho Research Foundation, Linden, N.J.
The incidence of fatal forms of erythroblastosis fetalis in the first-born can be
diminished by the simple measure of transfusing all Rh negative female patients,
even as infants, with Rh negative blood. Once a female patient is found to be Rh
negative, all subsequent transfusions must be carried out with Rh negative blood.
The indications are that sufficient human anti-Rh serums will become available for
the more extensive Rh tests required for the prevention of iso-immunization by
transfusion.