Blood, 1946, Vol. 1, No. 3, pp. 247-255.
© 1946 American Society of Hematology, Inc.
HEMATOLOGIC EFFECTS OF SPLENECTOMY IN STILL-CHAUFFARD-FELTY SYNDROME
A REPORT OF TWO CASES
JOHN S. HIRSCHBOECK M.D.1
1 Department of Medicine, Marquette University School of Medicine, and the Medical Department of Milwaukee County Hospital, Milwaukee, Wisconsin.
Two cases of Still-Chauffard-Felty syndrome treated by splenectomy are presented. One case has survived five years with complete hematologic restitution
and definite improvement in the arthritis. The second case expired six weeks after
splenectomy. Autopsy revealed portal vein thrombosis (pylephlebitis). Both
cases exhibited the blood manifestations associated with "hypersplenism."
In both cases splenectomy resulted in a return of the peripheral blood picture to
relative normality.