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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by SCHWARTZ, S. O. Articles by LEGERE, H. Search for Related Content PubMed Articles by SCHWARTZ, S. O. Articles by LEGERE, H. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Blood, 1946, Vol. 1, No. 4, pp. 307-316. © 1946 American Society of Hematology, Inc. TREATMENT OF LIVER EXTRACT SENSITIVITY STEVEN O. SCHWARTZ M.D.1 and HELEN LEGERE 1 1 From the Hektoen Institute for Medical Research of the Cook County Hospital, Chicago, Ill. Sensitivity reactions to the parenteral administration of liver extract are not uncommon. They were present in 68 of 396 patients (17 per cent) receiving liver therapy. The symptoms of sensitivity to liver extract are those of any foreign protein reaction. Various technics can be used to circumvent reactions and still maintain patients on adequate doses of liver extract. These methods are: A. Changing the "brand" or type of liver extract. B. Reducing the dose of liver extract. C. Desensitization with liver extract. D. Utilizing a histamine-protein complex as an antigen to produce histamine antibodies. The latter method was successful in 10 of 11 cases in which other methods had been without effect. CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

	Copyright © 1946 by American Society of Hematology         Online ISSN: 1528-0020