Blood, 1955, Vol. 10, No. 12, pp. 1256-1266.
© 1955 American Society of Hematology, Inc.
Mediterranean Anemia in the Negro
A Re-evaluation of Four Patients and Their Families
STEVEN O. SCHWARTZ 1 and
WILSON H. HARTZ JR. 1
1 Hematology Laboratory and the Hektoen Institute for Medical Research of
the Cook County Hospital, Chicago.
1. Four Negro patients and their families previously reported in 1949 as
examples of Mediterranean anemia were re-evaluated with regard to hemoglobin composition. The data have been presented.
2. Mediterranean anemia was confirmed in one entire family and in the index
case of another family.
3. Two entire families and one member of another family were found to
possess hemoglobin C.
4. Differential diagnostic points of Mediterranean anemia and hemoglobin C
disease are presented.
Submitted on June 20, 1955
Accepted on August 26, 1955