Blood, 1955, Vol. 10, No. 5, pp. 458-466.
© 1955 American Society of Hematology, Inc.
Comparative Incorporation of S35 L-Cystine and S35 Sodium
Sulfate by Normal and Leukemic Leukocytes
AUSTIN S. WEISBERGER 1 and
LEIF G. SUHRLAND 1
1 Department of Medicine, University Hospitals and the School of Medicine,
Western Reserve University.
1. Certain differences are demonstrated in the metabolic turnover of l-cystine
sulfur and inorganic sulfur by normal and leukemic leukocytes. These differences
are apparent both in vivo and in vitro and may be associated with factors peculiar
to the metabolism of leukemic leukocytes.
2. The incorporation of S35 l-cystine or S35 sodium sulfate by leukocytes appears to be associated primarily with the presence of immature granulocytes.
3. Both l-cystine (or l-cysteine) and sulfate may be of importance in the metabolism of leukocytes.
Submitted on July 31, 1954
Accepted on October 17, 1954