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Blood, 1955, Vol. 10, No. 9, pp. 926-932.
© 1955 American Society of Hematology, Inc.

Effect of Repetitive Exposures to Gamma Rays on the Hematopoietic System of the Rat

SIEGMUND J. BAUM 1, DONALD J. KIMELDORF 1, and ELLY M. JACOBSEN 1

1 Division of Biology and Medicine, U. S. Naval Radiological Defense Laboratory, San Francisco, California.

Rats were subjected to a series of one or more doses of 75 r gamma irradiation, at seven day intervals between exposures. Hematologic examinations were made following the last exposure in each series of irradiations. The maximum changes observed were, to a great extent, independent of the number of previous exposures, and appeared to reflect principally the effects of the last irradiation. These results were ascribed to the regenerative capacity of the hematopoietic system to recover during the seven day interval between radiation exposures.

Submitted on February 10, 1955
Accepted on March 5, 1955


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