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 Blood, 1 September 2006, Vol. 108, No. 5, pp. 1451-1460.
Prepublished online as a Blood First Edition Paper on April 25, 2006; DOI 10.1182/blood-2006-02-005017.

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REVIEW ARTICLES

Ocular adnexal lymphoma: a review of clinicopathologic features and treatment options

Didier Decaudin, Patricia de Cremoux, Anne Vincent-Salomon, Remi Dendale, and Livia Lumbroso-Le Rouic

From the Department of Clinical Hematology/Unité mixte de recherché (UMR) 144, Centre National de la Recherche Scientifique (CNRS), Institut Curie; the Department of Tumor Biology, Institut Curie; the Department of Radiation Oncology, Institut Curie; and the Department of Ophthalmology, Institut Curie, Paris, France.

The recent literature shows that interest in ocular adnexal lymphomas and their biologic and clinical characteristics—along with their possible association with Chlamydia psittaci infection and therapeutic management with rituximab or anti-Chlamydia psittaci antibiotic therapy—is considerable. These new data have modified the previously reported features of this disease and have made an updated review of the literature necessary. The aims of this review are to present the current knowledge on the biology of these lymphomas, their clinical features and prognostic factors, and the panel of all available treatment options.


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