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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by MCKINNEY, G. R. Articles by MARTIN, S. P. Search for Related Content PubMed PubMed Citation Articles by MCKINNEY, G. R. Articles by MARTIN, S. P. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Blood, 1956, Vol. 11, No. 5, pp. 455-459. © 1956 American Society of Hematology, Inc. The Effect of Certain Glycolytic Inhibitors on Aerobic Lactic Acid Production by Human Leukocytes in Vitro GORDON R. MCKINNEY 1 and SAMUEL P. MARTIN 1 1 Department of Pharmacology, West Virginia University School of Medicine, Morgantown, West Virginia, and the Department of Medicine, Duke University School of Medicine, Durham, North Carolina. Oxamic acid depressed aerobic lactic acid formation by normal, human leukocytes by only 20-25 per cent. Glyceraldehyde increased lactic acid production. Sorbose-1-phosphate was without effect. Iodacetate inhibited markedly, but fluoride depressed only in high concentrations. The significance of these findings regarding the mechanism of aerobic lactic acid formation by mature leukocytes is discussed. Submitted on August 23, 1955 Accepted on October 28, 1955 CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: S.-M. HONG, P. A. CIBIS, and M. CONSTANT Effects of Iodoacetic Acid on Ocular Inflammatory Responses Arch Ophthalmol, November 1, 1957; 58(5): 632 - 640. [Abstract] [PDF]

	Copyright © 1956 by American Society of Hematology         Online ISSN: 1528-0020