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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by SCHULMAN, I. Articles by CURRIMBHOY, Z. Search for Related Content PubMed PubMed Citation Articles by SCHULMAN, I. Articles by CURRIMBHOY, Z. Social Bookmarking                   What's this? Next Article  Blood, 1960, Vol. 16, No. 1, pp. 943-957. © 1960 American Society of Hematology, Inc. Studies on Thrombopoiesis. I. A Factor in Normal Human Plasma Required for Platelet Production; Chronic Thrombocytopenia Due to its Deficiency IRVING SCHULMAN 1, MILA PIERCE 1, ABBY LUKENS 1, and ZINET CURRIMBHOY 1 1 Children’s Memorial Hospital and the Departments of Pediatrics, Northwestern University Medical School, and The University of Chicago, Chicago, Ill. 1. A case of chronic thrombocytopenic purpura has been presented in which the pathogenesis appears to be due to congenital deficiency of a platelet-stimulating factor. 2. The factor exists in normal plasma and is stable on storage under normal blood banking conditions and on freezing. 3. The factor appears to act by stimulating megakaryocyte maturation and platelet production in an orderly and sequential manner. Submitted on August 15, 1959 Accepted on October 9, 1959 CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: J. E. Sadler Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura Blood, July 1, 2008; 112(1): 11 - 18. [Abstract] [Full Text] [PDF] G. G. Levy, D. G. Motto, and D. Ginsburg ADAMTS13 turns 3 Blood, July 1, 2005; 106(1): 11 - 17. [Abstract] [Full Text] [PDF] H.-M. Tsai Platelet Activation and the Formation of the Platelet Plug: Deficiency of ADAMTS13 Causes Thrombotic Thrombocytopenic Purpura Arterioscler. Thromb. Vasc. Biol., March 1, 2003; 23(3): 388 - 396. [Abstract] [Full Text] [PDF] R. Schneppenheim, U. Budde, F. Oyen, D. Angerhaus, V. Aumann, E. Drewke, W. Hassenpflug, J. Haberle, K. Kentouche, E. Kohne, et al. von Willebrand factor cleaving protease and ADAMTS13 mutations in childhood TTP Blood, March 1, 2003; 101(5): 1845 - 1850. [Abstract] [Full Text] [PDF] J. E. Sadler A new name in thrombosis, ADAMTS13 PNAS, September 3, 2002; 99(18): 11552 - 11554. [Full Text] [PDF] J. N. George, J. E. Sadler, and B. Lammle Platelets: Thrombotic Thrombocytopenic Purpura Hematology, January 1, 2002; 2002(1): 315 - 334. [Abstract] [Full Text] M. Miura, S. Koizumi, and H. Miyazaki Thrombopoietin in Upshaw-Schulman Syndrome Blood, June 15, 1997; 89(12): 4663 - 4663. [Full Text] [PDF] H. Lopas and S. F. Rabiner Thrombocytopenia Associated with Iron Deficiency Anemia: A Report of Five Cases Clinical Pediatrics, October 1, 1966; 5(10): 609 - 616. [PDF]

	Copyright © 1960 by American Society of Hematology         Online ISSN: 1528-0020