SEARCH:   Advanced

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by MIALE, J. B. Search for Related Content PubMed Articles by MIALE, J. B. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Blood, 1947, Vol. 2, No. 2, pp. 175-184. © 1947 American Society of Hematology, Inc. THE HEMATOLOGIC RESPONSE IN DOGS TO THE ADMINISTRATION OF ANTI SPLEEN SERUM JOHN B. MIALE M.D.1 1 Department of Pathology, the University of North Carolina, Chapel Hill, and the Laboratories of Watts Hospital, Durham, N. C. 1. Intravenous injection into dogs of rabbit anti-dog-spleen serum in doses of 0.04 cc./10 Kg. results in a significant increase in the mononuclear cells of the peripheral blood. 2. The rise in circulating mononuclears occurs promptly, with 24-48 hours, and is sustained, generally for 20 days. 3. A large dose of the same serum, 5.4 cc./10 Kg., exerted an opposite effect, poducing a significant decrease in circulating mononuclears. 4. The possible significance of these findings is discussed. CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

	Copyright © 1947 by American Society of Hematology         Online ISSN: 1528-0020