Blood, 1963, Vol. 21, No. 5, pp. 546-552.
© 1963 American Society of Hematology, Inc.
The Influence of Amino Acids on Iron Absorption
DONALD KROE 1,
THOMAS D. KINNEY 1,
NATHAN KAUFMAN 1, and
J. V. KLAVINS 1
1 Department of Pathology, Duke University Medical Center, Durham, N. C.
A series of experiments were devised to determine the effect of various
amino acids upon the absorption of iron from the gastrointestinal tract.
This was done by introducing single amino acids and Fe59 into isolated loops
of small intestine and measuring the serum for radioactivity and the uptake
of Fe59 by the liver. It was found that under the conditions of the experiments
all of the amino acids studied effected an increase in the serum iron and iron
deposition in the liver.
Submitted on August 13, 1962
Accepted on December 27, 1962