Blood, 1964, Vol. 23, No. 2, pp. 178-185.
© 1964 American Society of Hematology, Inc.
The Development of Platelet Factor 3 Activity by Latex Particles—An Interaction with Plasma
HERBERT I. HOROWITZ 1 and
AARON J. MARCUS 1
1 Department of Medicine, New York Hospital-Cornell Medical Center, and
the Hematology Section, New York V. A. Hospital, New York, N. Y.
Platelet factor 3 activity of polystyrene latex particles was found to be
absent when the particles were tested without prior incubation with plasma.
Following such incubation, the particles developed considerable but suboptimal activity. An interaction between the particles and some plasma
component(s) during the incubation period which gives rise to a labile type
of activity has been postulated.
Submitted on July 10, 1963
Accepted on August 6, 1963
