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Interacting populations affecting proliferation of leukemic cells in culture

MT Aye, JE Till and EA McCulloch

Peripheral blood cells from three patients with acute leukemic have been studied using a suspension culture method previously described.1 Cytogenetic studies in two of the patients permitted the identification of the proliferating cells in the cultures as being derived from a leukemic population. Cell separation studies using velocity sedimentation supported the concept that growth of the leukemic cells in culture is dependent on an interaction between two populations of leukemic cells.

Volume 45, Issue 4, pp. 485-493, 04/01/1975
Copyright © 1975 by The American Society of Hematology


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  Copyright © 1975 by American Society of Hematology         Online ISSN: 1528-0020