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Plasmapheresis in the treatment of thrombotic thrombocytopenic purpura

RM Bukowski, JW King and JS Hewlett

Two patients with thrombotic thrombocytopenic purpura (TTP) have recovered completely after intensive plasmapheresis. The mechanisms responsible for the improvement in these instances are most likely related to the removal of an inciting or damaging agent. The possibility that this agent may be an immune complex is discussed. Plasmapheresis appears to be useful therapy for some patients with this syndrome.

Volume 50, Issue 3, pp. 413-417, 09/01/1977
Copyright © 1977 by The American Society of Hematology


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