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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Stryckmans, P. A. Articles by Wybran, J. Search for Related Content PubMed PubMed Citation Articles by Stryckmans, P. A. Articles by Wybran, J. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Clonal origin of a T cell lymphoproliferative malignancy PA Stryckmans, L Debusscher, C Heyder-Bruckner, R Heimann, IM Mandelbaum and J Wybran A woman with a T cell lymphoproliferative malignacy and heterozhgosity at the X chromosome-linked locus for glucose-6-phosphate dehydrogenase (G-6PD) isoenzymes was studied to find the clonal origin of her circulating neoplastic T cells. The red blood cells, polymorphonuclear cells, whole mononuclear cells, and T cell-depleted mononuclear cells contained both A and B isoenzymes of G-6-PD. In contrast, the tumor cells, separated by using their capacity to form rosettes with sheep red blood cells, contained only the B isoenzyme of G-6-PD. This observation strongly suggests the monoclonality of this T cell malignancy. Volume 52, Issue 1, pp. 69-76, 07/01/1978 Copyright © 1978 by The American Society of Hematology CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: B. A. Brigham, P. A. Bunn Jr, J. E. Horton, G. P. Schechter, L. M. Wahl, E. C. Bradley, N. R. Dunnick, and M. J. Matthews Skeletal Manifestations in Cutaneous T-Cell Lymphomas Arch Dermatol, July 1, 1982; 118(7): 461 - 467. [Abstract] [PDF]

	Copyright © 1978 by American Society of Hematology         Online ISSN: 1528-0020