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Hemoglobin E trait reexamined: a cause of microcytosis and erythrocytosis

VF Fairbanks, GS Gilchrist, B Brimhall, JA Jereb and EC Goldston

The current Indochinese resettlement program in the United States has resulted in an increase in the number of persons with hemoglobin E trait. American physicians should be aware of the hematologic expressions of this innocuous condition. The hematologic manifestations of 21 persons with hemoglobin E trait were evaluated. The subjects were of Tai-dam, Vietnamese, Chinese, Laotian, and European origin. These studies showed uniform hematologic manifestations in hemoglobin E trait, characterized by slight microcytosis, by morphologic features resembling those of thalassemia minor, and often by increased erythrocyte count. Hemoglobin instability also was confirmed.

Volume 53, Issue 1, pp. 109-115, 01/01/1979
Copyright © 1979 by The American Society of Hematology


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