Hemoglobin E trait reexamined: a cause of microcytosis and erythrocytosis
VF Fairbanks, GS Gilchrist, B Brimhall, JA Jereb and EC Goldston
The current Indochinese resettlement program in the United States has
resulted in an increase in the number of persons with hemoglobin E trait.
American physicians should be aware of the hematologic expressions of this
innocuous condition. The hematologic manifestations of 21 persons with
hemoglobin E trait were evaluated. The subjects were of Tai-dam,
Vietnamese, Chinese, Laotian, and European origin. These studies showed
uniform hematologic manifestations in hemoglobin E trait, characterized by
slight microcytosis, by morphologic features resembling those of
thalassemia minor, and often by increased erythrocyte count. Hemoglobin
instability also was confirmed.
Volume 53,
Issue 1,
pp. 109-115,
01/01/1979
Copyright © 1979 by The American Society of Hematology