Granulocyte function during lithium therapy
MS Cohen, B Zakhireh, JA Metcalf and RK Root
Random migration, chemotaxis, phagocytosis, and bactericidal ability of
neutrophils from 5 patients receiving lithium carbonate were compared with
those of neutrophils from healthy donors. These cells functioned normally
in all respects. Neither sera from patients receiving lithium carbonate nor
the addition of lithium chloride to control cells in vitro significantly
altered their functional capacity. These findings suggest that neutrophil
function in patients receiving lithium therapy is preserved, and they
support the potential utility of this drug as a leukopoietic agent in
neutropenic states.
Volume 53,
Issue 5,
pp. 913-915,
05/01/1979
Copyright © 1979 by The American Society of Hematology
