Two cases of carcinoma of the lung characterized by a bone marrow agar
culture pattern resembling acute myeloid leukemia
JH McCarthy, JR Sullivan, B Ungar and D Metcalf
In vitro agar culture patterns of bone marrow cells in acute myeloid
leukemia may show several growth patterns, including cultures where no
colonies or clusters develop, cultures with varying numbers of clusters and
no colonies, or colony and cluster formation with an extremely high ratio
of clusters to colonies. Twelve cases of carcinoma of the lung are
described, of which two show an in vitro growth pattern of cluster
formation alone, characteristic of that seen in acute myeloid leukemia. The
remaining ten patients showed slightly reduced colony numbers compared to
normal.
Volume 54,
Issue 2,
pp. 530-533,
08/01/1979
Copyright © 1979 by The American Society of Hematology
