Blood online
Home About Blood Authors Subscriptions Permission Advertising Public Access contact us
 

 
Advanced
Current Issue
First Edition
Future Articles
Archives
Submit to Blood
Search
American Society of Hematology
Meeting Abstracts
Email Alerts
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Right arrow Rights and Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ramsay, N. K.
Right arrow Articles by Kersey, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ramsay, N. K.
Right arrow Articles by Kersey, J. H.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

arrow to previous article Previous Article  |  Table of Contents  |  Next Article next article arrow

Total lymphoid irradiation and cyclophosphamide as preparation for bone marrow transplantation in severe aplastic anemia

NK Ramsay, T Kim, ME Nesbit, W Krivit, PF Coccia, SH Levitt, WG Woods and JH Kersey

A new combination of total lymphoid irradiation and cyclophosphamide was used prior to bone marrow transplantation in an attempt to achieve decreased rejection rates and graft-versus-host disease. Nine previously transfused patients with severe aplastic anemia received marrow from an HLA-identical, MLC-compatible sibling following this preparative regimen. There were no episodes of graft rejection, and only one patient developed graft-versus-host disease. Of the 9 patients, 7 (78%) are surviving with a median follow-up of 400 days. The excellent results of this pretransplant combination of total lymphoid irradiation and cyclophosphamide warrants application of this regimen to a larger series of patients.

Volume 55, Issue 2, pp. 344-346, 02/01/1980
Copyright © 1980 by The American Society of Hematology


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 BloodHome page
A. Stucki, W. Leisenring, B. M. Sandmaier, J. Sanders, C. Anasetti, and R. Storb
Decreased Rejection and Improved Survival of First and Second Marrow Transplants for Severe Aplastic Anemia (A 26-Year Retrospective Analysis)
Blood, October 15, 1998; 92(8): 2742 - 2749.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
H. J. Deeg, W. Leisenring, R. Storb, J. Nims, M. E.D. Flowers, R. P. Witherspoon, J. Sanders, and K. M. Sullivan
Long-Term Outcome After Marrow Transplantation for Severe Aplastic Anemia
Blood, May 15, 1998; 91(10): 3637 - 3645.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
J. R. Passweg, G. Socie, W. Hinterberger, A. Bacigalupo, J. C. Biggs, B. M. Camitta, R. E. Champlin, R. P. Gale, E. Gluckman, E. C. Gordon-Smith, et al.
Bone Marrow Transplantation for Severe Aplastic Anemia: Has Outcome Improved?
Blood, July 15, 1997; 90(2): 858 - 864.
[Abstract] [Full Text] [PDF]

Home page
 ANN INTERN MEDHome page
R. P. GALE, R. E. CHAMPLIN, S. A. FEIG, and J. H. FITCHEN
Aplastic Anemia: Biology and Treatment
Ann Intern Med, October 1, 1981; 95(4): 477 - 494.
[Abstract] [PDF]


click for free articles
home about blood authors subscriptions permissions advertising public access contact us
  Copyright © 1980 by American Society of Hematology         Online ISSN: 1528-0020