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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Roelcke, D. Articles by Rauterberg, E. Search for Related Content PubMed PubMed Citation Articles by Roelcke, D. Articles by Rauterberg, E. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  A new human monoclonal cold agglutinin Sa recognizing terminal N- acetylneuraminyl groups on the cell surface D Roelcke, W Pruzanski, W Ebert, W Romer, E Fischer, V Lenhard and E Rauterberg A human homogeneous IgM/K cold agglutinin (CA) Sa is described, whose corresponding antigen on erythrocytes (RBC) was abolished by neuraminidase. This indicated that the antigen was related to N- acetylneuraminic acid, similar to Pr and Gd antigens. In contrast, this antigen was only partially destroyed by proteases, whereas Pr antigens are completely destroyed and Gd antigens are not influenced by proteases. Sa antibody activity was inhibited by sialyllactose NeuAc (alpha 2 leads to 3) (alpha 2 leads to 6) Gal (beta, 1 leads to 4) Glc like anti-Gd but in contrast to anti-Pr. The corresponding antigen was associated with an RBC membrane glycoprotein fraction like Pr, Sa is one of a spectrum of human monoclonal CA against cell surface neuraminyl groups. Volume 55, Issue 4, pp. 677-681, 04/01/1980 Copyright © 1980 by The American Society of Hematology CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

	Copyright © 1980 by American Society of Hematology         Online ISSN: 1528-0020