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T lymphocytes expressing human Ia-like antigens in infectious mononucleosis (IM)

E Tatsumi, K Kimura, Y Takiuchi, S Fukuhara, S Shirakawa, H Uchino, S Morikawa and J Minowada

In six patients with Epstein-Barr virus (EBV) induced infectious mononucleosis (IM) and in two patients with IM-like syndrome, peripheral blood lymphocytes in the acute and convalescent phase were tested for human la-like antigens as well as other cell surface markers. The major population of T lymphocytes in the acute phase showed la-like antigens, as detected by indirect immunofluorescence with heteroantisera, and the number of la-like antigen-positive T lymphocytes decreased with convalescence. The crossabsorption study indicated that the amount of la-like antigen on the surface of IM T cells was less than that of Raji cells.

Volume 56, Issue 3, pp. 383-387, 09/01/1980
Copyright © 1980 by The American Society of Hematology


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