|
|
 Previous Article | Table of Contents | Next Article 
Chronic graft-versus-host disease in 52 patients: adverse natural course
and successful treatment with combination immunosuppression
KM Sullivan, HM Shulman, R Storb, PL Weiden, RP Witherspoon, GB McDonald, MM Schubert, K Atkinson and ED Thomas
Fifty-two of 175 (30%) survivors of allogeneic marrow transplantation
developed chronic graft-versus-hose diseases (GVHD). Five with limited
chronic GVHD had an indolent clinical course with involvement of only the
skin and liver. Forty-seven with extensive chronic GVHD had an unfavorable
multiorgan disorder that resembled several autoimmune diseases. Thirteen
patients with extensive disease (group I) were not treated and only 2
survive with Karnofsky scores >- 70%. Mortality resulted from infections
and morbidity from sica syndrome, pulmonary and hepatic insufficiency,
scleroderma-like skin disease, and contractures. Another 13 (group II)
received a median of 8 mo prednisone and/or a brief course of antithymocyte
globulin, and 3 survive without disability. The other 21 (group III) were
treated with a combination of prednisone (1.0 mg/kg/q.o.d.) and either
cyclophosphamide, procarbazine, or azathioprine (all 1.5 mg/kg/day) for a
median of 13 mo. Combination therapy was well tolerated with only modest
myelotoxicity. Fifteen in group III had a good and 4 a fair response to
treatment while 2 with no response died. Azathioprine and prednisone was
the most effective regimen. All therapy has been discontinued in 12 group
III patients: GVHD returned in 5 (including 2 who died in spite of
retreatment) while 7 remain free of GVHD for a median of 11 (range 6-30) mo
observation. Only I group III survivor is disabled and 16 of the original
21 are alive 2-4 yr after transplant with Karnofsky scores of 70%-100%.
Thus, combination immmunosuppression appears to favorably affect and, in
some cases, premanently arrest the adverse natural course of extensive
chronic GVHD.
Volume 57,
Issue 2,
pp. 267-276,
02/01/1981
Copyright © 1981 by The American Society of Hematology
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati What's this?
This article has been cited by other articles:
|
|
|
|
 
H. E. Heslop, K. S. Slobod, M. A. Pule, G. A. Hale, A. Rousseau, C. A. Smith, C. M. Bollard, H. Liu, M.-F. Wu, R. J. Rochester, et al.
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
Blood,
February 4, 2010;
115(5):
925 - 935.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. A. Jacobsohn, A. L. Gilman, A. Rademaker, B. Browning, M. Grimley, L. Lehmann, E. R. Nemecek, K. Thormann, K. R. Schultz, and G. B. Vogelsang
Evaluation of pentostatin in corticosteroid-refractory chronic graft-versus-host disease in children: a Pediatric Blood and Marrow Transplant Consortium study
Blood,
November 12, 2009;
114(20):
4354 - 4360.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Dodero, C. Carniti, A. Raganato, A. Vendramin, L. Farina, F. Spina, C. Carlo-Stella, S. Di Terlizzi, M. Milanesi, P. Longoni, et al.
Haploidentical stem cell transplantation after a reduced-intensity conditioning regimen for the treatment of advanced hematologic malignancies: posttransplantation CD8-depleted donor lymphocyte infusions contribute to improve T-cell recovery
Blood,
May 7, 2009;
113(19):
4771 - 4779.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Horger, W. Bethge, A. Boss, M. Fenchel, C. D. Claussen, M. Schmalzing, and W. Vogel
Musculocutaneous Chronic Graft-Versus-Host Disease: MRI Follow-Up of Patients Undergoing Immunosuppressive Therapy
Am. J. Roentgenol.,
May 1, 2009;
192(5):
1401 - 1406.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Farina, C. Carniti, A. Dodero, A. Vendramin, A. Raganato, F. Spina, F. Patriarca, F. Narni, F. Benedetti, A. Olivieri, et al.
Qualitative and quantitative polymerase chain reaction monitoring of minimal residual disease in relapsed chronic lymphocytic leukemia: early assessment can predict long-term outcome after reduced intensity allogeneic transplantation
Haematologica,
May 1, 2009;
94(5):
654 - 662.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. W. Chien, M. J. Boeckh, J. A. Hansen, and J. G. Clark
Lipopolysaccharide binding protein promoter variants influence the risk for Gram-negative bacteremia and mortality after allogeneic hematopoietic cell transplantation
Blood,
February 15, 2008;
111(4):
2462 - 2469.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Kebriaei, M. A. Detry, S. Giralt, A. Carrasco-Yalan, A. Anagnostopoulos, D. Couriel, I. F. Khouri, P. Anderlini, C. Hosing, A. Alousi, et al.
Long-term follow-up of allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning for patients with chronic myeloid leukemia
Blood,
November 1, 2007;
110(9):
3456 - 3462.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. A. Jacobsohn, A. R. Chen, M. Zahurak, S. Piantadosi, V. Anders, J. Bolanos-Meade, M. Higman, J. Margolis, M. Kaup, and G. B. Vogelsang
Phase II Study of Pentostatin in Patients With Corticosteroid-Refractory Chronic Graft-Versus-Host Disease
J. Clin. Oncol.,
September 20, 2007;
25(27):
4255 - 4261.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Chang, B. E. Storer, B. L. Scott, E. M. Bryant, H. M. Shulman, M. E. Flowers, B. M. Sandmaier, R. P. Witherspoon, R. A. Nash, J. E. Sanders, et al.
Hematopoietic cell transplantation in patients with myelodysplastic syndrome or acute myeloid leukemia arising from myelodysplastic syndrome: similar outcomes in patients with de novo disease and disease following prior therapy or antecedent hematologic disorders
Blood,
August 15, 2007;
110(4):
1379 - 1387.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Jaffe, E. B. Papadopoulos, J. W. Young, R. J. O'Reilly, S. Prockop, N. A. Kernan, A. Jakubowski, F. Boulad, M.-A. Perales, H. Castro-Malaspina, et al.
Immunogenicity of recombinant hepatitis B vaccine (rHBV) in recipients of unrelated or related allogeneic hematopoietic cell (HC) transplants
Blood,
October 1, 2006;
108(7):
2470 - 2475.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. R. Couriel, C. Hosing, R. Saliba, E. J. Shpall, P. Anderlini, B. Rhodes, V. Smith, I. Khouri, S. Giralt, M. de Lima, et al.
Extracorporeal photochemotherapy for the treatment of steroid-resistant chronic GVHD
Blood,
April 15, 2006;
107(8):
3074 - 3080.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. Corradini, F. Zallio, J. Mariotti, L. Farina, M. Bregni, P. Valagussa, F. Ciceri, A. Bacigalupo, A. Dodero, M. Lucesole, et al.
Effect of Age and Previous Autologous Transplantation on Nonrelapse Mortality and Survival in Patients Treated With Reduced-Intensity Conditioning and Allografting for Advanced Hematologic Malignancies
J. Clin. Oncol.,
September 20, 2005;
23(27):
6690 - 6698.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. J. Lee
New approaches for preventing and treating chronic graft-versus-host disease
Blood,
June 1, 2005;
105(11):
4200 - 4206.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Lee, Y.-J. Kim, C.-K. Min, H.-J. Kim, K.-S. Eom, D.-W. Kim, J.-W. Lee, W.-S. Min, and C.-C. Kim
The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia
Blood,
May 1, 2005;
105(9):
3449 - 3457.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. E. Sanders, H. J. Im, P. A. Hoffmeister, T. A. Gooley, A. E. Woolfrey, P. A. Carpenter, R. G. Andrews, E. M. Bryant, and F. R. Appelbaum
Allogeneic hematopoietic cell transplantation for infants with acute lymphoblastic leukemia
Blood,
May 1, 2005;
105(9):
3749 - 3756.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Iwasaki
Recent Advances in the Treatment of Graft-Versus-Host Disease
Clin. Med. Res.,
November 1, 2004;
2(4):
243 - 252.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. E. Anderson, J. M. McNiff, C. Matte, I. Athanasiadis, W. D. Shlomchik, and M. J. Shlomchik
Recipient CD4+ T cells that survive irradiation regulate chronic graft-versus-host disease
Blood,
September 1, 2004;
104(5):
1565 - 1573.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R.M. Nagler and A. Nagler
The Molecular Basis of Salivary Gland Involvement in Graft-vs.-Host Disease
Journal of Dental Research,
February 1, 2004;
83(2):
98 - 103.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. S. B. Randolph, T. A. Gooley, E. H. Warren, F. R. Appelbaum, and S. R. Riddell
Female donors contribute to a selective graft-versus-leukemia effect in male recipients of HLA-matched, related hematopoietic stem cell transplants
Blood,
January 1, 2004;
103(1):
347 - 352.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. J. Deeg, T. A. Gooley, M. E. D. Flowers, G. E. Sale, J. T. Slattery, C. Anasetti, T. R. Chauncey, K. Doney, G. E. Georges, H.-P. Kiem, et al.
Allogeneic hematopoietic stem cell transplantation for myelofibrosis
Blood,
December 1, 2003;
102(12):
3912 - 3918.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Akpek, S. J. Lee, M. E. Flowers, S. Z. Pavletic, M. Arora, S. Lee, S. Piantadosi, K. A. Guthrie, J. C. Lynch, A. Takatu, et al.
Performance of a new clinical grading system for chronic graft-versus-host disease: a multicenter study
Blood,
August 1, 2003;
102(3):
802 - 809.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. A. Perez-Simon, M. Diez-Campelo, R. Martino, A. Sureda, D. Caballero, C. Canizo, S. Brunet, A. Altes, L. Vazquez, J. Sierra, et al.
Impact of CD34+ cell dose on the outcome of patients undergoing reduced-intensity-conditioning allogeneic peripheral blood stem cell transplantation
Blood,
August 1, 2003;
102(3):
1108 - 1113.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. W. Chien, P. J. Martin, T. A. Gooley, M. E. Flowers, S. R. Heckbert, W. G. Nichols, and J. G. Clark
Airflow Obstruction after Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation
Am. J. Respir. Crit. Care Med.,
July 15, 2003;
168(2):
208 - 214.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Mohty, J.-O. Bay, C. Faucher, B. Choufi, K. Bilger, O. Tournilhac, N. Vey, A.-M. Stoppa, D. Coso, C. Chabannon, et al.
Graft-versus-host disease following allogeneic transplantation from HLA-identical sibling with antithymocyte globulin-based reduced-intensity preparative regimen
Blood,
July 15, 2003;
102(2):
470 - 476.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. P. Radich, T. Gooley, W. Bensinger, T. Chauncey, R. Clift, M. Flowers, P. Martin, J. Slattery, D. Sultan, and F. R. Appelbaum
HLA-matched related hematopoietic cell transplantation for chronic-phase CML using a targeted busulfan and cyclophosphamide preparative regimen
Blood,
July 1, 2003;
102(1):
31 - 35.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. J. Winston, R. T. Maziarz, P. H. Chandrasekar, H. M. Lazarus, M. Goldman, J. L. Blumer, G. J. Leitz, and M. C. Territo
Intravenous and Oral Itraconazole versus Intravenous and Oral Fluconazole for Long-Term Antifungal Prophylaxis in Allogeneic Hematopoietic Stem-Cell Transplant Recipients: A Multicenter, Randomized Trial
Ann Intern Med,
May 6, 2003;
138(9):
705 - 713.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
V. Rocha, R. F. Franco, R. Porcher, H. Bittencourt, W. A. Silva Jr, A. Latouche, A. Devergie, H. Esperou, P. Ribaud, G. Socie, et al.
Host defense and inflammatory gene polymorphisms are associated with outcomes after HLA-identical sibling bone marrow transplantation
Blood,
December 1, 2002;
100(12):
3908 - 3918.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Mohty, M. Kuentz, M. Michallet, J.-H. Bourhis, N. Milpied, L. Sutton, J.-P. Jouet, M. Attal, P. Bordigoni, J.-Y. Cahn, et al.
Chronic graft-versus-host disease after allogeneic blood stem cell transplantation: long-term results of a randomized study
Blood,
October 16, 2002;
100(9):
3128 - 3134.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. A. Perez-Simon, P. D. Kottaridis, R. Martino, C. Craddock, D. Caballero, R. Chopra, J. Garcia-Conde, D. W. Milligan, S. Schey, A. Urbano-Ispizua, et al.
Nonmyeloablative transplantation with or without alemtuzumab: comparison between 2 prospective studies in patients with lymphoproliferative disorders
Blood,
October 16, 2002;
100(9):
3121 - 3127.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Ruutu, B. Eriksson, K. Remes, E. Juvonen, L. Volin, M. Remberger, T. Parkkali, H. Hagglund, and O. Ringden
Ursodeoxycholic acid for the prevention of hepatic complications in allogeneic stem cell transplantation
Blood,
August 28, 2002;
100(6):
1977 - 1983.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Zecca, A. Prete, R. Rondelli, E. Lanino, A. Balduzzi, C. Messina, F. Fagioli, F. Porta, C. Favre, A. Pession, et al.
Chronic graft-versus-host disease in children: incidence, risk factors, and impact on outcome
Blood,
July 30, 2002;
100(4):
1192 - 1200.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. H. Antin
Long-Term Care after Hematopoietic-Cell Transplantation in Adults
N. Engl. J. Med.,
July 4, 2002;
347(1):
36 - 42.
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. F. Penas, M. Jones-Caballero, M. Aragues, J. Fernandez-Herrera, J. Fraga, and A. Garcia-Diez
Sclerodermatous Graft-vs-Host Disease: Clinical and Pathological Study of 17 Patients
Arch Dermatol,
July 1, 2002;
138(7):
924 - 934.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Koc, W. Leisenring, M. E. D. Flowers, C. Anasetti, H. J. Deeg, R. A. Nash, J. E. Sanders, R. P. Witherspoon, R. Storb, F. R. Appelbaum, et al.
Therapy for chronic graft-versus-host disease: a randomized trial comparing cyclosporine plus prednisone versus prednisone alone
Blood,
June 17, 2002;
100(1):
48 - 51.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Bittencourt, V. Rocha, S. Chevret, G. Socie, H. Esperou, A. Devergie, L. Dal Cortivo, J.-P. Marolleau, F. Garnier, P. Ribaud, et al.
Association of CD34 cell dose with hematopoietic recovery, infections, and other outcomes after HLA-identical sibling bone marrow transplantation
Blood,
April 15, 2002;
99(8):
2726 - 2733.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. E. Woolfrey, C. Anasetti, B. Storer, K. Doney, L. A. Milner, E. L. Sievers, P. Carpenter, P. Martin, E. Petersdorf, F. R. Appelbaum, et al.
Factors associated with outcome after unrelated marrow transplantation for treatment of acute lymphoblastic leukemia in children
Blood,
March 15, 2002;
99(6):
2002 - 2008.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. G. Maloney, B. M. Sandmaier, S. Mackinnon, and J. A. Shizuru
Non-Myeloablative Transplantation
Hematology,
January 1, 2002;
2002(1):
392 - 421.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
E. Kansu, T. Gooley, M. E. D. Flowers, C. Anasetti, H. J. Deeg, R. A. Nash, J. E. Sanders, R. P. Witherspoon, F. R. Appelbaum, R. Storb, et al.
Administration of cyclosporine for 24 months compared with 6 months for prevention of chronic graft-versus-host disease: a prospective randomized clinical trial
Blood,
December 15, 2001;
98(13):
3868 - 3870.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
V. T. Ho and R. J. Soiffer
The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation
Blood,
December 1, 2001;
98(12):
3192 - 3204.
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Akpek, M. L. Zahurak, S. Piantadosi, J. Margolis, J. Doherty, R. Davidson, and G. B. Vogelsang
Development of a prognostic model for grading chronic graft-versus-host disease
Blood,
March 1, 2001;
97(5):
1219 - 1226.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Ruutu, L. Volin, T. Parkkali, E. Juvonen, and E. Elonen
Cyclosporine, methotrexate, and methylprednisolone compared with cyclosporine and methotrexate for the prevention of graft-versus-host disease in bone marrow transplantation from HLA-identical sibling donor: a prospective randomized study
Blood,
October 1, 2000;
96(7):
2391 - 2398.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. T. Greinix, B. Volc-Platzer, P. Kalhs, G. Fischer, A. Rosenmayr, F. Keil, H. Honigsmann, and R. M. Knobler
Extracorporeal photochemotherapy in the treatment of severe steroid-refractory acute graft-versus-host disease: a pilot study
Blood,
October 1, 2000;
96(7):
2426 - 2431.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. A. Nash, J. H. Antin, C. Karanes, J. W. Fay, B. R. Avalos, A. M. Yeager, D. Przepiorka, S. Davies, F. B. Petersen, P. Bartels, et al.
Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors
Blood,
September 15, 2000;
96(6):
2062 - 2068.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Green, E. Clarke, L. Hunt, A. Canterbury, A. Lankester, G. Hale, H. Waldmann, S. Goodman, J. M. Cornish, D. I. Marks, et al.
Children With Acute Lymphoblastic Leukemia Who Receive T-Cell-Depleted HLA Mismatched Marrow Allografts From Unrelated Donors Have an Increased Incidence of Primary Graft Failure but a Similar Overall Transplant Outcome
Blood,
October 1, 1999;
94(7):
2236 - 2246.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. I. Strasser, K. M. Sullivan, D. Myerson, C. L. Spurgeon, B. Storer, H. G. Schoch, C. S. Murakami, and G. B. McDonald
Cirrhosis of the Liver in Long-Term Marrow Transplant Survivors
Blood,
May 15, 1999;
93(10):
3259 - 3266.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
O. Ringden, M. Remberger, T. Ruutu, J. Nikoskelainen, L. Volin, L. Vindelov, T. Parkkali, S. Lenhoff, B. Sallerfors, L. Mellander, et al.
Increased Risk of Chronic Graft-Versus-Host Disease, Obstructive Bronchiolitis, and Alopecia With Busulfan Versus Total Body Irradiation: Long-Term Results of a Randomized Trial in Allogeneic Marrow Recipients With Leukemia
Blood,
April 1, 1999;
93(7):
2196 - 2201.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. E. Woolfrey, T. A. Gooley, E. L. Sievers, L. A. Milner, R. G. Andrews, M. Walters, P. Hoffmeister, J. A. Hansen, C. Anasetti, E. Bryant, et al.
Bone Marrow Transplantation for Children Less Than 2 Years of Age With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Blood,
November 15, 1998;
92(10):
3546 - 3556.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. T. Greinix, B. Volc-Platzer, W. Rabitsch, B. Gmeinhart, C. Guevara-Pineda, P. Kalhs, J. Krutmann, H. Honigsmann, M. Ciovica, and R. M. Knobler
Successful Use of Extracorporeal Photochemotherapy in the Treatment of Severe Acute and Chronic Graft-Versus-Host Disease
Blood,
November 1, 1998;
92(9):
3098 - 3104.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Stucki, W. Leisenring, B. M. Sandmaier, J. Sanders, C. Anasetti, and R. Storb
Decreased Rejection and Improved Survival of First and Second Marrow Transplants for Severe Aplastic Anemia (A 26-Year Retrospective Analysis)
Blood,
October 15, 1998;
92(8):
2742 - 2749.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
V. Ratanatharathorn, R. A. Nash, D. Przepiorka, S. M. Devine, J. L. Klein, D. Weisdorf, J. W. Fay, A. Nademanee, J. H. Antin, N. P. Christiansen, et al.
Phase III Study Comparing Methotrexate and Tacrolimus (Prograf, FK506) With Methotrexate and Cyclosporine for Graft-Versus-Host Disease Prophylaxis After HLA-Identical Sibling Bone Marrow Transplantation
Blood,
October 1, 1998;
92(7):
2303 - 2314.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. J. Morton, T. Gooley, J. A. Hansen, F. R. Appelbaum, B. Bruemmer, J. W. Bjerke, R. Clift, P. J. Martin, E. W. Petersdorf, J. E. Sanders, et al.
Association Between Pretransplant Interferon-alpha and Outcome After Unrelated Donor Marrow Transplantation for Chronic Myelogenous Leukemia in Chronic Phase
Blood,
July 15, 1998;
92(2):
394 - 401.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. J. Deeg, W. Leisenring, R. Storb, J. Nims, M. E.D. Flowers, R. P. Witherspoon, J. Sanders, and K. M. Sullivan
Long-Term Outcome After Marrow Transplantation for Severe Aplastic Anemia
Blood,
May 15, 1998;
91(10):
3637 - 3645.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Aractingi and O. Chosidow
Cutaneous Graft-versus-Host Disease
Arch Dermatol,
May 1, 1998;
134(5):
602 - 612.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Rodriguez-Inigo, J.-F. Tomas, V. Gomez-Garcia de Soria, J. Bartolome, I. Pinilla, M.-J. Amaro, V. Carreno, and J.-M. Fernandez-Ranada
Hepatitis C and G Virus Infection and Liver Dysfunction After Allogeneic Bone Marrow Transplantation: Results From a Prospective Study
Blood,
August 1, 1997;
90(3):
1326 - 1331.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. J. Deeg, D. Lin, W. Leisenring, M. Boeckh, C. Anasetti, F. R. Appelbaum, T. R. Chauncey, K. Doney, M. Flowers, P. Martin, et al.
Cyclosporine or Cyclosporine Plus Methylprednisolone for Prophylaxis of Graft-Versus-Host Disease: A Prospective, Randomized Trial
Blood,
May 15, 1997;
89(10):
3880 - 3887.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S.-B. Woo, S. J. Lee, and M. M. Schubert
Graft-vs.-Host Disease
Critical Reviews in Oral Biology & Medicine,
January 1, 1997;
8(2):
201 - 216.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Behar, N. J. Chao, D. D. Hiraki, S. Krishnaswamy, B. W. Brown, J. L. Zehnder, and F. C. Grumet
Polymorphism of Adhesion Molecule CD31 and Its Role in Acute Graft-Versus-Host Disease
N. Engl. J. Med.,
February 1, 1996;
334(5):
286 - 291.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. M. Coskuncan, D. A. Jabs, J. P. Dunn, J. A. Haller, W. R. Green, G. B. Vogelsang, and G. W. Santos
The Eye in Bone Marrow Transplantation: VI. Retinal Complications
Arch Ophthalmol,
March 1, 1994;
112(3):
372 - 379.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. P. Dunn, D. A. Jabs, J. Wingard, C. Enger, G. Vogelsang, and G. Santos
Bone Marrow Transplantation and Cataract Development
Arch Ophthalmol,
October 1, 1993;
111(10):
1367 - 1373.
[Abstract]
[PDF]
|
|
|
|
|
|
|
R. H. Fried, C. S. Murakami, L. D. Fisher, R. A. Willson, K. M. Sullivan, and G. B. McDonald
Ursodeoxycholic Acid Treatment of Refractory Chronic Graft-versus-Host Disease of the Liver
Ann Intern Med,
April 15, 1992;
116(8):
624 - 629.
[Abstract]
[PDF]
|
|
|
|
|
|
|
R. M. Jampel, E. R. Farmer, G. B. Vogelsang, J. Wingard, G. W. Santos, and W. L. Morison
PUVA Therapy for Chronic Cutaneous Graft-vs-Host Disease
Arch Dermatol,
November 1, 1991;
127(11):
1673 - 1678.
[Abstract]
[PDF]
|
|
|
|
|
|
|
M. H. Sayegh, N. A. Fine, J. L. Smith, H. G. Rennke, E. L. Milford, and N. L. Tilney
Immunologic Tolerance to Renal Allografts after Bone Marrow Transplants from the Same Donors
Ann Intern Med,
June 1, 1991;
114(11):
954 - 955.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. G. Clark, S. W. Crawford, D. K. Madtes, and K. M. Sullivan
Obstructive Lung Disease after Allogeneic Marrow Transplantation: Clinical Presentation and Course
Ann Intern Med,
September 1, 1989;
111(5):
368 - 376.
[Abstract]
[PDF]
|
|
|
|
|
|
|
D. A. Jabs, J. Wingard, W. R. Green, E. R. Farmer, G. Vogelsang, and R. Saral
The Eye in Bone Marrow Transplantation: III. Conjunctival Graft-vs-Host Disease
Arch Ophthalmol,
September 1, 1989;
107(9):
1343 - 1348.
[Abstract]
[PDF]
|
|
|
|
|
|
|
P. Kalhs, S. Panzer, K. Kletter, E. Minar, M. Stain-Kos, R. Walter, K. Lechner, and W. Hinterberger
Functional Asplenia after Bone Marrow Transplantation: A Late Complication Related to Extensive Chronic Graft-Versus-Host Disease
Ann Intern Med,
September 15, 1988;
109(6):
461 - 464.
[Abstract]
[PDF]
|
|
|
|
|
|
|
N. R. Howe and P. G. Lang
Squamous Cell Carcinoma of the Sole in a Patient With Chronic Graft-vs-Host Disease
Arch Dermatol,
August 1, 1988;
124(8):
1244 - 1245.
[Abstract]
[PDF]
|
|
|
|
|
|
|
J. G. CLARK, D. A. SCHWARTZ, N. FLOURNOY, K. M. SULLIVAN, S. W. CRAWFORD, and E. D. THOMAS
Risk Factors for Airflow Obstruction in Recipients of Bone Marrow Transplants
Ann Intern Med,
November 1, 1987;
107(5):
648 - 656.
[Abstract]
[PDF]
|
|
|
|
|
|
|
C. ANASETTI, K. C. DONEY, R. STORB, J. D. MEYERS, V. T. FAREWELL, C. D. BUCKNER, F. R. APPELBAUM, K. M. SULLIVAN, R. A. CLIFT, H. J. DEEG, et al.
Marrow Transplantation for Severe Aplastic Anemia: Long-Term Outcome in Fifty "Untransfused" Patients
Ann Intern Med,
April 1, 1986;
104(4):
461 - 466.
[Abstract]
[PDF]
|
|
|
|
|
|
|
A. P. Barrett and A. M. Bilous
Oral Patterns of Acute and Chronic Graft-v-Host Disease
Arch Dermatol,
November 1, 1984;
120(11):
1461 - 1465.
[Abstract]
[PDF]
|
|
|
|
|
|
|
M. M. Schubert, K. M. Sullivan, T. H. Morton, K. T. Izutsu, D. E. Peterson, N. Flournoy, E. L. Truelove, G. E. Sale, C. D. Buckner, R. Storb, et al.
Oral Manifestations of Chronic Graft-v-Host Disease
Arch Intern Med,
August 1, 1984;
144(8):
1591 - 1595.
[Abstract]
[PDF]
|
|
|
|
|
|
|
W. D. James and R. B. Odom
Graft-v-Host Disease
Arch Dermatol,
August 1, 1983;
119(8):
683 - 689.
[Abstract]
[PDF]
|
|
|
|
|
|
|
M. K. Jack, G. M. Jack, G. E. Sale, H. M. Shulman, and K. M. Sullivan
Ocular Manifestations of Graft-v-Host Disease
Arch Ophthalmol,
July 1, 1983;
101(7):
1080 - 1084.
[Abstract]
[PDF]
|
|
|
|
|
|
|
R. STORB, R. L. PRENTICE, K. M. SULLIVAN, H. M. SHULMAN, H. J. DEEG, K. C. DONEY, C. D. BUCKNER, R. A. CLIFT, R. P. WITHERSPOON, F. A. APPELBAUM, et al.
Predictive Factors in Chronic Graft-Versus-Host Disease in Patients with Aplastic Anemia Treated by Marrow Transplantation from HLA-Identical Siblings
Ann Intern Med,
April 1, 1983;
98(4):
461 - 466.
[Abstract]
[PDF]
|
|
|
|
|
|
|
L. W. Hirst, D. A. Jabs, P. J. Tutschka, W. R. Green, and G. W. Santos
The Eye in Bone Marrow Transplantation: I. Clinical Study
Arch Ophthalmol,
April 1, 1983;
101(4):
580 - 584.
[Abstract]
[PDF]
|
|
|
|
|
|
|
R. P. GALE, R. E. CHAMPLIN, S. A. FEIG, and J. H. FITCHEN
Aplastic Anemia: Biology and Treatment
Ann Intern Med,
October 1, 1981;
95(4):
477 - 494.
[Abstract]
[PDF]
|
|
|
|
|
