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Decreased deformability of erythrocytes from smokers

JM Norton and PW Rand

The deformability of erythrocytes from smoking and non-smoking human subjects was examined by filtration through 3-mu pores and capillary viscometry of cell suspensions. In both cases, small but significant differences were found between the two groups that are consistent with a reduction in the surface area-to-volume ratio and/or a diminished membrane flexibility in erythrocyte from smokers. Additional evidence suggests that these findings represent a chronic rather than an acute effect of smoking on erythrocyte deformability.

Volume 57, Issue 4, pp. 671-674, 04/01/1981
Copyright © 1981 by The American Society of Hematology


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  Copyright © 1981 by American Society of Hematology         Online ISSN: 1528-0020