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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Calcagno, M. Articles by Weiss-Steider, B. Search for Related Content PubMed PubMed Citation Articles by Calcagno, M. Articles by Weiss-Steider, B. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Evidence of the existence of a factor that induces Fc receptors on bone marrow cells M Calcagno, JR Perez, MG Waldo, G Cabrera and B Weiss-Steider The existence of a molecule responsible for the induction of Fc receptor (FcR) on bone marrow cells (FcR inducer, FcRI) is demonstrated in conditioned media from the macrophage-like cell line WR19M.1 activated by bacterial lipopolysaccharides. The molecular weight obtained from molecular sieving chromatography in gel and density gradient sedimentation is found to be 18,500 daltons and 16,000 daltons, respectively, with an isoelectric pH of 7.4. The factor is found to be thermolabile and trypsin sensitive. The macrophage and granulocyte inducer (MGI), also known as colony-stimulating factor (CSF) or colony-stimulating activity (CSA), is identified from the same source and found to have a molecular weight and an isoelectric pH different from FcRI. The fractions that contained the MGI did not induce FcR on bone marrow cells, while the fractions rich in FcRI did not induce colony formation. Volume 59, Issue 4, pp. 756-760, 04/01/1982 Copyright © 1982 by The American Society of Hematology CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

	Copyright © 1982 by American Society of Hematology         Online ISSN: 1528-0020