|
|
Next Article 
Induction of differentiation of human acute myelogenous leukemia cells:
therapeutic implications
HP Koeffler
A prominent phenotypic abnormality of human acute myelogenous leukemia
cells is the inability of the cells to differentiate to functional mature
cells; instead, the cells are blocked at an early stage of development and
remain in the proliferative pool and rapidly accumulate. Investigation of
the induction of myeloid leukemic cell differentiation has made recent
advances with the development of several human myelogenous leukemia cell
lines. The lines provide models to study the biology of myeloid
differentiation and to identify inducers of differentiation of myeloid
leukemic blood cells. This review critically examines the inducers of
leukemic cell differentiation and their potential therapeutic importance.
Volume 62,
Issue 4,
pp. 709-721,
10/01/1983
Copyright © 1983 by The American Society of Hematology
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati What's this?
This article has been cited by other articles:
|
|
|
|
 
X. Wang, R. Patel, and G. P. Studzinski
hKSR-2, a vitamin D-regulated gene, inhibits apoptosis in arabinocytosine-treated HL60 leukemia cells
Mol. Cancer Ther.,
September 1, 2008;
7(9):
2798 - 2806.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Yaneva, S. Kippenberger, N. Wang, Q. Su, M. McGarvey, A. Nazarian, L. Lacomis, H. Erdjument-Bromage, and P. Tempst
PU.1 and a TTTAAA Element in the Myeloid Defensin-1 Promoter Create an Operational TATA Box That Can Impose Cell Specificity onto TFIID Function.
J. Immunol.,
June 1, 2006;
176(11):
6906 - 6917.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. F. Gombart, N. Borregaard, and H. P. Koeffler
Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3
FASEB J,
July 1, 2005;
19(9):
1067 - 1077.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J.-N. Bastie, N. Balitrand, F. Guidez, I. Guillemot, J. Larghero, C. Calabresse, C. Chomienne, and L. Delva
1{alpha},25-Dihydroxyvitamin D3 Transrepresses Retinoic Acid Transcriptional Activity via Vitamin D Receptor in Myeloid Cells
Mol. Endocrinol.,
November 1, 2004;
18(11):
2685 - 2699.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Konakahara, K. Ohashi, K. Mizuno, K. Itoh, and T. Tsuji
CD29 integrin- and LIMK1/cofilin-mediated actin reorganization regulates the migration of haematopoietic progenitor cells underneath bone marrow stromal cells
Genes Cells,
April 1, 2004;
9(4):
345 - 358.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. L. Ackerman and P. Cresswell
Regulation of MHC Class I Transport in Human Dendritic Cells and the Dendritic-Like Cell Line KG-1
J. Immunol.,
April 15, 2003;
170(8):
4178 - 4188.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
W.-K. Hofmann and H. P. Koeffler
Differentiation Therapy for Myelodysplastic Syndrome
Clin. Cancer Res.,
April 1, 2002;
8(4):
939 - 941.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. W. Rooney and K. L. Calame
TIF1beta functions as a coactivator for C/EBPbeta and is required for induced differentiation in the myelomonocytic cell line U937
Genes & Dev.,
November 15, 2001;
15(22):
3023 - 3038.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
X. Hu, W. E. Janssen, L. C. Moscinski, M. Bryington, A. Dangsupa, N. Rezai-Zadeh, B. A. Babbin, and K. S. Zuckerman
An I{kappa}B{alpha} Inhibitor Causes Leukemia Cell Death through a p38 MAP Kinase-dependent, NF-{kappa}B-independent Mechanism
Cancer Res.,
August 1, 2001;
61(16):
6290 - 6296.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
W Ding, S Gao, and R. Scott
Senescence represses the nuclear localization of the serum response factor and differentiation regulates its nuclear localization with lineage specificity
J. Cell Sci.,
January 3, 2001;
114(5):
1011 - 1018.
[Abstract]
[PDF]
|
|
|
|
|
|
|
T. Ikezoe, E. S. Daar, J.-i. Hisatake, H. Taguchi, and H. P. Koeffler
HIV-1 protease inhibitors decrease proliferation and induce differentiation of human myelocytic leukemia cells
Blood,
November 15, 2000;
96(10):
3553 - 3559.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Hayashi, Y. Honma, N. Niitsu, T. Taki, F. Bessho, M. Sako, T. Mori, M. Yanagisawa, K. Tsuji, and T. Nakahata
SN-1, A Novel Leukemic Cell Line with t(11;16)(q23;p13): Myeloid Characteristics and Resistance to Retinoids and Vitamin D3
Cancer Res.,
February 1, 2000;
60(4):
1139 - 1145.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
R. Gautier, A. Jiang, V. Rousseau, R. Dornburg, and T. Jaffredo
Avian Reticuloendotheliosis Virus Strain A and Spleen Necrosis Virus Do Not Infect Human Cells
J. Virol.,
January 1, 2000;
74(1):
518 - 522.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
J. L. Moran, D. Siegel, and D. Ross
A potential mechanism underlying the increased susceptibility of individuals with a polymorphism in NAD(P)H:quinone oxidoreductase 1 (NQO1) to benzene toxicity
PNAS,
July 6, 1999;
96(14):
8150 - 8155.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Yamamoto, K. Tsukahara, Y. Kanaoka, S. Jinno, and H. Okayama
Isolation of a Mammalian Homologue of a Fission Yeast Differentiation Regulator
Mol. Cell. Biol.,
May 1, 1999;
19(5):
3829 - 3841.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Muto, M. Kizaki, K. Yamato, Y. Kawai, M. Kamata-Matsushita, H. Ueno, M. Ohguchi, T. Nishihara, H. P. Koeffler, and Y. Ikeda
1,25-Dihydroxyvitamin D3 Induces Differentiation of a Retinoic Acid-Resistant Acute Promyelocytic Leukemia Cell Line (UF-1) Associated With Expression of p21WAF1/CIP1 and p27KIP1
Blood,
April 1, 1999;
93(7):
2225 - 2233.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Shiohara, M. I. Dawson, P. D. Hobbs, N. Sawai, T. Higuchi, K. Koike, A. Komiyama, and H. P. Koeffler
Effects of Novel RAR- and RXR-Selective Retinoids on Myeloid Leukemic Proliferation and Differentiation In Vitro
Blood,
March 15, 1999;
93(6):
2057 - 2066.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Francis, R. Ramakrishna, W. Holloway, and B. O. Palsson
Two New Pseudopod Morphologies Displayed by the Human Hematopoietic KG1a Progenitor Cell Line and by Primary Human CD34+ Cells
Blood,
November 15, 1998;
92(10):
3616 - 3623.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Ma, Q. Su, and P. Tempst
Differentiation-stimulated Activity Binds an ETS-like, Essential Regulatory Element in the Human Promyelocytic defensin-1 Promoter
J. Biol. Chem.,
April 10, 1998;
273(15):
8727 - 8740.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Matsushita, M. Kizaki, H. Kobayashi, H. Ueno, A. Muto, N. Takayama, N. Awaya, K. Kinjo, Y. Hattori, and Y. Ikeda
Restoration of Retinoid Sensitivity by MDR1 Ribozymes in Retinoic Acid-Resistant Myeloid Leukemic Cells
Blood,
April 1, 1998;
91(7):
2452 - 2458.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. Tsuji, I. Waga, K. Tezuka, M. Kamada, K. Yatsunami, and H. Kodama
Integrin beta 2 (CD18)-Mediated Cell Proliferation of HEL Cells on a Hematopoietic-Supportive Bone Marrow Stromal Cell Line, HESS-5 Cells
Blood,
February 15, 1998;
91(4):
1263 - 1271.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Shirafuji, S. Takahashi, S. Matsuda, and S. Asano
Mitochondrial Antisense RNA for Cytochrome C Oxidase (MARCO) Can Induce Morphologic Changes and Cell Death in Human Hematopoietic Cell Lines
Blood,
December 1, 1997;
90(11):
4567 - 4577.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. J. Ketley, P. D. Allen, S. M. Kelsey, and A. C. Newland
Modulation of Idarubicin-Induced Apoptosis in Human Acute Myeloid Leukemia Blasts by All-Trans Retinoic Acid, 1,25(OH)2 Vitamin D3, and Granulocyte-Macrophage Colony-Stimulating Factor
Blood,
December 1, 1997;
90(11):
4578 - 4587.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Burger, M. Wick, and R. Muller
Lineage-specific regulation of cell cycle gene expression in differentiating myeloid cells
J. Cell Sci.,
July 1, 1994;
107(7):
2047 - 2054.
[Abstract]
[PDF]
|
|
|
|
|
