|
|
 Previous Article | Table of Contents | Next Article 
A Hodgkin cell-specific antigen is expressed on a subset of auto- and
alloactivated T (helper) lymphoblasts
R Andreesen, J Osterholz, GW Lohr and KJ Bross
A Hodgkin cell-specific antigen detected by the monoclonal antibody Ki- 1
was found on T helper lymphocytes after activation by autologous and
allogeneic stimulator cells. About 50% of lymphoblasts generated by auto-
and alloactivation reacted with the antibody. In contrast, only less than
6% of lymphoblasts stimulated with Con-A, phytohemagglutinin (PHA), or
protein A, and none of lymphoblasts activated by oxidative mitogenesis,
expressed this antigen. Among several permanent cell lines tested, the
K562, MOLT-4, HL-60, and EBV transformed B lymphoblastoid cells reacted
with the Ki-1 antibody. The results may indicate possible relationships
between the autoreactive subset of T lymphocytes and the pathogenesis of
Hodgkin's disease.
Volume 63,
Issue 6,
pp. 1299-1302,
06/01/1984
Copyright © 1984 by The American Society of Hematology
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati What's this?
This article has been cited by other articles:
|
|
|
|
 
E. S. Jaffe, N. L. Harris, H. Stein, and P. G. Isaacson
Classification of lymphoid neoplasms: the microscope as a tool for disease discovery
Blood,
December 1, 2008;
112(12):
4384 - 4399.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S.-Y. Nam, Y.-H. Kim, J.-S. Do, Y.-H. Choi, H.-J. Seo, H.-K. Yi, P.-H. Hwang, C.-H. Song, H.-K. Lee, J.-S. Kim, et al.
CD30 supports lung inflammation
Int. Immunol.,
February 1, 2008;
20(2):
177 - 184.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. J. Croager, A. M. Gout, and L. J. Abraham
Involvement of Sp1 and Microsatellite Repressor Sequences in the Transcriptional Control of the Human CD30 Gene
Am. J. Pathol.,
May 1, 2000;
156(5):
1723 - 1731.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. W. Gedrich, M. C. Gilfillan, C. S. Duckett, J. L. Van Dongen, and C. B. Thompson
CD30 Contains Two Binding Sites with Different Specificities for Members of the Tumor Necrosis Factor Receptor-associated Factor Family of Signal Transducing Proteins
J. Biol. Chem.,
May 31, 1996;
271(22):
12852 - 12858.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
O. P. Sangueza, J. Galloway, P. A. Eagan, R. M. Braziel, and M. L. Gulley
Absence of Epstein-Barr Virus in Lymphomatoid Papulosis: An Immunohistochemical and In Situ Hybridization Study
Arch Dermatol,
March 1, 1996;
132(3):
279 - 282.
[Abstract]
[PDF]
|
|
|
|
|
|
|
H. Sugimoto, F. Nakayama, T. Yamauchi, Y. Tokura, K. Iwatsuki, M. Takigawa, M. Yamada, and M. Maeda
Ki-1+ Cutaneous Lymphoma: Gene Rearrangement Analysis of Tumor Cells in Tissue and Short-term Culture of a Patient
Arch Dermatol,
March 1, 1988;
124(3):
405 - 408.
[Abstract]
[PDF]
|
|
|
|
|
|
|
M. E. Kadin
Characteristic Immunologic Profile of Large Atypical Cells in Lymphomatoid Papulosis: Possible Implications for Histogenesis and Relationship to Other Diseases
Arch Dermatol,
December 1, 1986;
122(12):
1388 - 1390.
[Abstract]
[PDF]
|
|
|
|
|
|
|
Y. Tokura, M. Takigawa, T. Oku, and M. Yamada
Lymphomatoid Papulosis: Histologic and Immunohistochemical Studies in a Patient With a Scaly Pigmented Eruption
Arch Dermatol,
December 1, 1986;
122(12):
1400 - 1405.
[Abstract]
[PDF]
|
|
|
|
|
|
|
M. Greaves
Differentiation-linked leukemogenesis in lymphocytes
Science,
November 7, 1986;
234(4777):
697 - 704.
[Abstract]
[PDF]
|
|
|
|
|
