|
|
Previous Article | Table of Contents | Next Article 
Acute monoblastic leukemia in infancy and early childhood: successful
treatment with an epipodophyllotoxin
LF Odom and EM Gordon
Four of five infants and young children with acute monoblastic leukemia, a
disease that heretofore has been highly refractory to therapy, were
successfully treated with sequential infusions of a podophyllin derivative
employed as a single agent over a protracted period of time. In three of
the five children, monocytic leukemia cutis was present at birth. Treatment
was begun in two of them when the disease had progressed to systemic
involvement at a few months of age, and in the third when disease was still
localized. The other two children were 11 and 18 months of age at initial
presentation with widespread disease. Four children are off therapy 11
months, 26 months, 5 years, and 6 years, respectively.
Volume 64,
Issue 4,
pp. 875-882,
10/01/1984
Copyright © 1984 by The American Society of Hematology

CiteULike Connotea Del.icio.us Digg Reddit Technorati What's this?
This article has been cited by other articles:

|
 |

|
 |
 
S. Meshinchi and R. J. Arceci
Prognostic Factors and Risk-Based Therapy in Pediatric Acute Myeloid Leukemia
Oncologist,
March 1, 2007;
12(3):
341 - 355.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
M. S. Tallman, H. T. Kim, E. Paietta, J. M. Bennett, G. Dewald, P. A. Cassileth, P. H. Wiernik, and J. M. Rowe
Acute Monocytic Leukemia (French-American-British classification M5) Does Not Have a Worse Prognosis Than Other Subtypes of Acute Myeloid Leukemia: A Report From the Eastern Cooperative Oncology Group
J. Clin. Oncol.,
April 1, 2004;
22(7):
1276 - 1286.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. E. Rubnitz, S. C. Raimondi, X. Tong, D. K. Srivastava, B. I. Razzouk, S. A. Shurtleff, J. R. Downing, C.-H. Pui, R. C. Ribeiro, and F. G. Behm
Favorable Impact of the t(9;11) in Childhood Acute Myeloid Leukemia
J. Clin. Oncol.,
May 1, 2002;
20(9):
2302 - 2309.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
H. Kawasaki, K. Isoyama, M. Eguchi, S. Hibi, N. Kinukawa, Y. Kosaka, T. Oda, M. Oda, S.-i. Nishimura, M. Imaizumi, et al.
Superior outcome of infant acute myeloid leukemia with intensive chemotherapy: results of the Japan Infant Leukemia Study Group
Blood,
December 15, 2001;
98(13):
3589 - 3594.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. M. Zwaan, G.-J. L. Kaspers, R. Pieters, N. L. R.-V. Woerden, M. L. den Boer, R. Wunsche, M. M. A. Rottier, K. Hahlen, E. R. van Wering, G. E. Janka-Schaub, et al.
Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia
Blood,
October 15, 2000;
96(8):
2879 - 2886.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
O. Legrand, G. Simonin, A. Beauchamp-Nicoud, R. Zittoun, and J.-P. Marie
Simultaneous Activity of MRP1 and Pgp Is Correlated With In Vitro Resistance to Daunorubicin and With In Vivo Resistance in Adult Acute Myeloid Leukemia
Blood,
August 1, 1999;
94(3):
1046 - 1056.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
C. A. Felix and B. J. Lange
Leukemia in Infants
Oncologist,
June 1, 1999;
4(3):
225 - 240.
[Abstract]
[Full Text]
|
 |
|

|
 |

|
 |
 
I. M. Hann, R. F. Stevens, A. H. Goldstone, J. K.H. Rees, K. Wheatley, R. G. Gray, and A. K. Burnett
Randomized Comparison of DAT Versus ADE as Induction Chemotherapy in Children and Younger Adults With Acute Myeloid Leukemia. Results of the Medical Research Council's 10th AML Trial (MRC AML10)
Blood,
April 1, 1997;
89(7):
2311 - 2318.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
K. S. Resnik and B. B. Brod
Leukemia Cutis in Congenital Leukemia: Analysis and Review of the World Literature With Report of an Additional Case
Arch Dermatol,
October 1, 1993;
129(10):
1301 - 1306.
[Abstract]
[PDF]
|
 |
|
|
|