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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Groopman, J. E. Articles by Gallo, R. Search for Related Content PubMed PubMed Citation Articles by Groopman, J. E. Articles by Gallo, R. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Antibody seronegative human T-lymphotropic virus type III (HTLV-III)- infected patients with acquired immunodeficiency syndrome or related disorders JE Groopman, PI Hartzband, L Shulman, SZ Salahuddin, MG Sarngadharan, MF McLane, M Essex and R Gallo The human T-lymphotropic virus type III (HTLV-III) is the primary cause of the acquired immunodeficiency syndrome (AIDS) and related disorders (ARC). Prior studies have reported that nearly all symptomatic patients with AIDS or ARC manifest antibody to HTLV-III. This observation has engendered efforts to screen for HTLV-III, especially prior to blood donation, with assays for antibody to HTLV-III. We report the first two cases, one with AIDS and one with ARC, that are HTLV-III virus positive but antibody negative. Accurate diagnosis of HTLV-III infection in some cases may require direct virus culture or tests for antigen. In addition, lack of HTLV-III antibody may indicate an atypical clinical course of AIDS. Volume 66, Issue 3, pp. 742-744, 09/01/1985 Copyright © 1985 by The American Society of Hematology CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: M. S. Kruskall and J. Umlas Acquired Immunodeficiency Syndrome and Directed Blood Donations: A Dilemma for American Medicine Arch Surg, January 1, 1988; 123(1): 23 - 25. [Abstract] [PDF] D. P. Francis and J. Chin The Prevention of Acquired Immunodeficiency Syndrome in the United States: An Objective Strategy for Medicine, Public Health, Business, and the Community JAMA, March 13, 1987; 257(10): 1357 - 1366. [Abstract] [PDF] B. Rabkin and M. S. Rabkin Individual and Institutional Liability for Transfusion-Acquired Diseases: An Update JAMA, October 24, 1986; 256(16): 2242 - 2243. [Abstract] [PDF] P. R. Gustafson Prevention of HTLV-III Infection JAMA, July 18, 1986; 256(3): 346 - 347. [Abstract] [PDF] R. Yomtovian HTLV-III Antibody Testing: The False-Negative Rate JAMA, February 7, 1986; 255(5): 609 - 609. [Abstract] [PDF] K. H. MAYER, A. M. STODDARD, J. McCUSKER, D. AYOTTE, R. FERRIANI, and J. E. GROOPMAN Human T-Lymphotropic Virus Type III in High-Risk, Antibody-Negative Homosexual Men Ann Intern Med, February 1, 1986; 104(2): 194 - 196. [Abstract] [PDF]

	Copyright © 1985 by American Society of Hematology         Online ISSN: 1528-0020