|
|
 Previous Article | Table of Contents | Next Article 
Serum transferrin receptor as a new index of erythropoiesis
Y Kohgo, Y Niitsu, H Kondo, J Kato, N Tsushima, K Sasaki, M Hirayama, T Numata, T Nishisato and I Urushizaki
Department of Internal Medicine, Sapporo Medical College, Japan.
Serum transferrin receptors were measured by a sandwich radioimmunoassay
procedure in patients with iron deficiency anemia, autoimmune hemolytic
anemia and aplastic anemia. The mean circulating transferrin receptor
concentration of normal subjects and patients with iron deficiency anemia,
autoimmune hemolytic anemia and aplastic anemia are 253 +/- 82 ng/mL, 730
+/- 391 ng/mL, 1,426 +/- 1,079 ng/mL, and 182 +/- 39 ng/mL, respectively.
The values for those with iron deficiency anemia and autoimmune hemolytic
anemia were significantly higher than that of normal controls and the
values for those with aplastic anemia were lower than that of normal
controls. After iron supplementation in iron deficiency anemia, the serum
transferrin receptor values increased twofold over those of pretreatment
values. This increase parallels an increase in peripheral reticulocytes.
Therefore, the number of circulating transferrin receptors in anemic
patients may reflect the level of bone marrow erythropoiesis and is a
potentially useful new index for red cell production.
Volume 70,
Issue 6,
pp. 1955-1958,
12/01/1987
Copyright © 1987 by The American Society of Hematology
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati What's this?
This article has been cited by other articles:
|
|
|
|
 
A. Maria Verner, J. Manderson, T. R J Lappin, D. R McCance, H. L Halliday, and D. G Sweet
Influence of maternal diabetes mellitus on fetal iron status
Arch. Dis. Child. Fetal Neonatal Ed.,
September 1, 2007;
92(5):
F399 - F401.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Knox-Macaulay, D. Gravell, and F. Elender
Serum Transferrin Receptor Status of Healthy Adult Arabs
Ann. Clin. Lab. Sci.,
January 1, 2007;
37(1):
57 - 62.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Pak, M. A. Lopez, V. Gabayan, T. Ganz, and S. Rivera
Suppression of hepcidin during anemia requires erythropoietic activity
Blood,
December 1, 2006;
108(12):
3730 - 3735.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Haiden, J. Schwindt, F. Cardona, A. Berger, K. Klebermass, M. Wald, C. Kohlhauser-Vollmuth, B. Jilma, and A. Pollak
Effects of a Combined Therapy of Erythropoietin, Iron, Folate, and Vitamin B12 on the Transfusion Requirements of Extremely Low Birth Weight Infants
Pediatrics,
November 1, 2006;
118(5):
2004 - 2013.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
N. Haiden, K. Klebermass, F. Cardona, J. Schwindt, A. Berger, C. Kohlhauser-Vollmuth, B. Jilma, and A. Pollak
A Randomized, Controlled Trial of the Effects of Adding Vitamin B12 and Folate to Erythropoietin for the Treatment of Anemia of Prematurity
Pediatrics,
July 1, 2006;
118(1):
180 - 188.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. E Cusick, J. M Tielsch, M. Ramsan, J. K Jape, S. Sazawal, R. E Black, and R. J Stoltzfus
Short-term effects of vitamin A and antimalarial treatment on erythropoiesis in severely anemic Zanzibari preschool children
Am. J. Clinical Nutrition,
August 1, 2005;
82(2):
406 - 412.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. B Zimmermann, L. Molinari, F. Staubli-Asobayire, S. Y Hess, N. Chaouki, P. Adou, and R. F Hurrell
Serum transferrin receptor and zinc protoporphyrin as indicators of iron status in African children
Am. J. Clinical Nutrition,
March 1, 2005;
81(3):
615 - 623.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. Vikstedt, P. von Lode, T. Takala, K. Irjala, O. Peltola, K. Pettersson, and P. Suominen
Rapid One-Step Immunofluorometric Assay for Measuring Soluble Transferrin Receptor in Whole Blood
Clin. Chem.,
October 1, 2004;
50(10):
1831 - 1833.
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. W. Choi and S. H. Pai
Associations Between Serum Transferrin Receptor Concentrations and Erythropoietic Activities According to Body Iron Status
Ann. Clin. Lab. Sci.,
July 1, 2003;
33(3):
279 - 284.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
O. Hernell and B. Lonnerdal
Iron status of infants fed low-iron formula: no effect of added bovine lactoferrin or nucleotides
Am. J. Clinical Nutrition,
October 1, 2002;
76(4):
858 - 864.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D.-C. Tarng and T.-P. Huang
Determinants of circulating soluble transferrin receptor level in chronic haemodialysis patients
Nephrol. Dial. Transplant.,
June 1, 2002;
17(6):
1063 - 1069.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y O Schumacher, A Schmid, D Konig, and A Berg
Effects of exercise on soluble transferrin receptor and other variables of the iron status
Br. J. Sports Med.,
June 1, 2002;
36(3):
195 - 199.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Rimon, S. Levy, A. Sapir, G. Gelzer, R. Peled, D. Ergas, and Z. M. Sthoeger
Diagnosis of Iron Deficiency Anemia in the Elderly by Transferrin Receptor-Ferritin Index
Arch Intern Med,
February 25, 2002;
162(4):
445 - 449.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. E. Mast, M. A. Blinder, Q. Lu, S. Flax, and D. J. Dietzen
Clinical utility of the reticulocyte hemoglobin content in the diagnosis of iron deficiency
Blood,
February 15, 2002;
99(4):
1489 - 1491.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Kato, M. Kobune, Y. Kohgo, K. Fujikawa, R. Takimoto, Y. Torimoto, Y. Ito, M. Bessho, T. Hotta, A. Hikawa, et al.
Ratio of Transferrin (Tf) to Tf-Receptor Complex in Circulation Differs Depending on Tf Iron Saturation
Clin. Chem.,
January 1, 2002;
48(1):
181 - 183.
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. Van den Bosch, J. Van den Bossche, C. Wagner, P. De Schouwer, M. Van De Vyvere, and H. Neels
Determination of Iron Metabolism-related Reference Values in a Healthy Adult Population
Clin. Chem.,
August 1, 2001;
47(8):
1465 - 1467.
[Full Text]
[PDF]
|
|
|
|
|
|
|
M. Olivares, T. Walter, J. D Cook, E. Hertrampf, and F. Pizarro
Usefulness of serum transferrin receptor and serum ferritin in diagnosis of iron deficiency in infancy
Am. J. Clinical Nutrition,
November 1, 2000;
72(5):
1191 - 1195.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. SATO, N. YAMAUCHI, M. TAKAHASHI, K. SASAKI, J. FUKAURA, H. NEDA, S. FUJII, M. HIRAYAMA, Y. ITOH, Y. KOSHITA, et al.
In vivo gene delivery to tumor cells by transferrin-streptavidin-DNA conjugate
FASEB J,
October 1, 2000;
14(13):
2108 - 2118.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
L. T. Goodnough, B. Skikne, and C. Brugnara
Erythropoietin, iron, and erythropoiesis
Blood,
August 1, 2000;
96(3):
823 - 833.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
R. J. Stoltzfus, H. M. Chwaya, A. Montresor, M. Albonico, L. Savioli, and J. M. Tielsch
Malaria, Hookworms and Recent Fever Are Related to Anemia and Iron Status Indicators in 0- to 5-y Old Zanzibari Children and These Relationships Change with Age
J. Nutr.,
July 1, 2000;
130(7):
1724 - 1733.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
E. J. Harthoorn-Lasthuizen, P. vant Sant, J. Lindemans, and M. M.A.C. Langenhuijsen
Serum Transferrin Receptor and Erythrocyte Zinc Protoporphyrin in Patients with Anemia,
Clin. Chem.,
May 1, 2000;
46(5):
719 - 722.
[Full Text]
[PDF]
|
|
|
|
|
|
|
B. S. Skikne
Circulating Transferrin Receptor Assay—Coming of Age
Clin. Chem.,
January 1, 1998;
44(1):
7 - 9.
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Khumalo, Z. A. R. Gomo, V. M. Moyo, V. R. Gordeuk, T. Saungweme, T. A. Rouault, and I. T. Gangaidzo
Serum transferrin receptors are decreased in the presence of iron overload
Clin. Chem.,
January 1, 1998;
44(1):
40 - 44.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. E. Mast, M. A. Blinder, A. M. Gronowski, C. Chumley, and M. G. Scott
Clinical utility of the soluble transferrin receptor and comparison with serum ferritin in several populations
Clin. Chem.,
January 1, 1998;
44(1):
45 - 51.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. Gimferrer, J. Ubeda, M.T. Royo, G.J. Marigo, N. Marco, N. Fernandez, A. Oliver, R. Padros, and I. Gich
Serum Transferrin Receptor Levels in Different Stages of Iron Deficiency
Blood,
August 1, 1997;
90(3):
1332 - 1333.
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Punnonen, K. Irjala, and A. Rajamaki
Serum Transferrin Receptor and Its Ratio to Serum Ferritin in the Diagnosis of Iron Deficiency
Blood,
February 1, 1997;
89(3):
1052 - 1057.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
