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Therapy of chronic idiopathic thrombocytopenic purpura in adults [see comments]

P Berchtold and R McMillan

Department of Molecular and Experimental Medicine, Research Institute of Scripps Clinic, La Jolla, CA 92037.

Chronic ITP is a common hematologic illness. Approximately three fourths of the patients respond to corticosteroids or splenectomy and need no further treatment. Patients refractory to these two therapeutic approaches are relatively resistant to present forms of treatment and are at much greater risk for morbidity and mortality. Future clinical studies evaluating therapy in this refractory group would be best performed in a cooperative group setting in which large numbers of patients could be treated in a prospective randomized manner.

Volume 74, Issue 7, pp. 2309-2317, 11/15/1989
Copyright © 1989 by The American Society of Hematology


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