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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Trent, R. J. Articles by Harris, P. C. Search for Related Content PubMed PubMed Citation Articles by Trent, R. J. Articles by Harris, P. C. Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  Molecular and hematologic characterization of Scottish-Irish type (epsilon gamma delta beta)zero thalassemia RJ Trent, BG Williams, A Kearney, T Wilkinson and PC Harris Clinical Immunology Research Centre, University of Sydney, New South Wales, Australia. The DNA deletion associated with an example of (epsilon gamma delta beta)zero thalassemia (Scottish-Irish type) was characterized. The deletion is approximately 205 kb in length and involves the epsilon, G gamma, A gamma, delta, and beta globin genes. The breakpoint is located 263 bp 3' to exon 3 of the beta globin gene. An LI (KpnI) repeat element approximately 320 bp in size is found at the 3' end of the novel DNA sequence. Different clinical phenotypes for three heterozygous neonates suggest that the deletion alone does not predict severity of (epsilon gamma delta beta)zero thalassemia at this age. Volume 76, Issue 10, pp. 2132-2138, 11/15/1990 Copyright © 1990 by The American Society of Hematology CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

	Copyright © 1990 by American Society of Hematology         Online ISSN: 1528-0020