SEARCH:   Advanced

This Article Full Text Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Ponka, P Search for Related Content PubMed PubMed Citation Articles by Ponka, P Related Collections Review Articles Social Bookmarking                   What's this? Next Article  Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells P Ponka Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada. Volume 89, Issue 1, pp. 1-25, 01/01/1997 Copyright © 1997 by The American Society of Hematology CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This article has been cited by other articles: A. Iolascon, L. De Falco, and C. Beaumont Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis Haematologica, March 1, 2009; 94(3): 395 - 408. [Abstract] [Full Text] [PDF] M. Tian, D. R. Campagna, L. S. Woodward, M. J. Justice, and M. D. Fleming hem6: an ENU-induced recessive hypochromic microcytic anemia mutation in the mouse Blood, November 15, 2008; 112(10): 4308 - 4313. [Abstract] [Full Text] [PDF] A. K. Agarwal, T. Xu, M. R. Jacob, Q. Feng, M. C. Lorenz, L. A. Walker, and A. M. Clark Role of Heme in the Antifungal Activity of the Azaoxoaporphine Alkaloid Sampangine Eukaryot. Cell, February 1, 2008; 7(2): 387 - 400. [Abstract] [Full Text] [PDF] K. Otogawa, T. Ogawa, R. Shiga, K. Nakatani, K. Ikeda, Y. Nakajima, and N. Kawada Attenuation of acute and chronic liver injury in rats by iron-deficient diet Am J Physiol Regulatory Integrative Comp Physiol, February 1, 2008; 294(2): R311 - R320. [Abstract] [Full Text] [PDF] F. Missirlis, S. Kosmidis, T. Brody, M. Mavrakis, S. Holmberg, W. F. Odenwald, E. M. C. Skoulakis, and T. A. Rouault Homeostatic Mechanisms for Iron Storage Revealed by Genetic Manipulations and Live Imaging of Drosophila Ferritin Genetics, September 1, 2007; 177(1): 89 - 100. [Abstract] [Full Text] [PDF] C. Camaschella, A. Campanella, L. De Falco, L. Boschetto, R. Merlini, L. Silvestri, S. Levi, and A. Iolascon The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload Blood, August 15, 2007; 110(4): 1353 - 1358. [Abstract] [Full Text] [PDF] A. D. Sheftel, A.-S. Zhang, C. Brown, O. S. Shirihai, and P. Ponka Direct interorganellar transfer of iron from endosome to mitochondrion Blood, July 1, 2007; 110(1): 125 - 132. [Abstract] [Full Text] [PDF] J.-J. Chen Regulation of protein synthesis by the heme-regulated eIF2{alpha} kinase: relevance to anemias Blood, April 1, 2007; 109(7): 2693 - 2699. [Abstract] [Full Text] [PDF] V Nunia, G Sancheti, and P K Goyal Protection of Swiss albino mice against whole-body gamma irradiation by diltiazem Br. J. Radiol., February 1, 2007; 80(950): 77 - 84. [Abstract] [Full Text] [PDF] M.-A. Alyanakian, Y. Taes, M. Bensaid, B. Segovia, P. Aucouturier, J.-D. Rain, J. Delanghe, B. Varet, and C. Beaumont Monoclonal immunoglobulin with antitransferrin activity: a rare cause of hypersideremia with increased transferrin saturation Blood, January 1, 2007; 109(1): 359 - 361. [Abstract] [Full Text] [PDF] D. Su, J. M. May, M. J. Koury, and H. Asard Human Erythrocyte Membranes Contain a Cytochrome b561 That May Be Involved in Extracellular Ascorbate Recycling J. Biol. Chem., December 29, 2006; 281(52): 39852 - 39859. [Abstract] [Full Text] [PDF] G. Nie, G. Chen, A. D. Sheftel, K. Pantopoulos, and P. Ponka In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin Blood, October 1, 2006; 108(7): 2428 - 2434. [Abstract] [Full Text] [PDF] J. J. Andresen, N. I. Shafi, W. Durante, and R. M. Bryan Jr. Effects of carbon monoxide and heme oxygenase inhibitors in cerebral vessels of rats and mice Am J Physiol Heart Circ Physiol, July 1, 2006; 291(1): H223 - H230. [Abstract] [Full Text] [PDF] O. Nakajima, S. Okano, H. Harada, T. Kusaka, X. Gao, T. Hosoya, N. Suzuki, S. Takahashi, and M. Yamamoto Transgenic rescue of erythroid 5-aminolevulinate synthase-deficient mice results in the formation of ring sideroblasts and siderocytes Genes Cells, June 1, 2006; 11(6): 685 - 700. [Abstract] [Full Text] [PDF] M. Schranzhofer, M. Schifrer, J. A. Cabrera, S. Kopp, P. Chiba, H. Beug, and E. W. Mullner Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis Blood, May 15, 2006; 107(10): 4159 - 4167. [Abstract] [Full Text] [PDF] D. S. Kalinowski and D. R. Richardson The Evolution of Iron Chelators for the Treatment of Iron Overload Disease and Cancer Pharmacol. Rev., December 1, 2005; 57(4): 547 - 583. [Abstract] [Full Text] [PDF] M. M. Rhodes, P. Kopsombut, M. C. Bondurant, J. O. Price, and M. J. Koury Bcl-xL prevents apoptosis of late-stage erythroblasts but does not mediate the antiapoptotic effect of erythropoietin Blood, September 1, 2005; 106(5): 1857 - 1863. [Abstract] [Full Text] [PDF] S. S. Cooperman, E. G. Meyron-Holtz, H. Olivierre-Wilson, M. C. Ghosh, J. P. McConnell, and T. A. Rouault Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2 Blood, August 1, 2005; 106(3): 1084 - 1091. [Abstract] [Full Text] [PDF] C. R. Chitambar Cellular iron metabolism: mitochondria in the spotlight Blood, March 1, 2005; 105(5): 1844 - 1845. [Full Text] [PDF] I. Napier, P. Ponka, and D. R. Richardson Iron trafficking in the mitochondrion: novel pathways revealed by disease Blood, March 1, 2005; 105(5): 1867 - 1874. [Abstract] [Full Text] [PDF] G. Nie, A. D. Sheftel, S. F. Kim, and P. Ponka Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis Blood, March 1, 2005; 105(5): 2161 - 2167. [Abstract] [Full Text] [PDF] B. Sturm, U. Bistrich, M. Schranzhofer, J. P. Sarsero, U. Rauen, B. Scheiber-Mojdehkar, H. de Groot, P. Ioannou, and F. Petrat Friedreich's Ataxia, No Changes in Mitochondrial Labile Iron in Human Lymphoblasts and Fibroblasts: A DECREASE IN ANTIOXIDATIVE CAPACITY? J. Biol. Chem., February 25, 2005; 280(8): 6701 - 6708. [Abstract] [Full Text] [PDF] R. Ferreira, K. Ohneda, M. Yamamoto, and S. Philipsen GATA1 Function, a Paradigm for Transcription Factors in Hematopoiesis Mol. Cell. Biol., February 15, 2005; 25(4): 1215 - 1227. [Full Text] [PDF] A.-S. Zhang, A. D. Sheftel, and P. Ponka Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria Blood, January 1, 2005; 105(1): 368 - 375. [Abstract] [Full Text] [PDF] J.-Y. Li, G. Ram, K. Gast, X. Chen, K. Barasch, K. Mori, K. Schmidt-Ott, J. Wang, H.-C. Kuo, C. Savage-Dunn, et al. Detection of intracellular iron by its regulatory effect Am J Physiol Cell Physiol, December 1, 2004; 287(6): C1547 - C1559. [Abstract] [Full Text] [PDF] A. Campanella, G. Isaya, H. A. O'Neill, P. Santambrogio, A. Cozzi, P. Arosio, and S. Levi The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast Hum. Mol. Genet., October 1, 2004; 13(19): 2279 - 2288. [Abstract] [Full Text] [PDF] J. Pauluhn Subacute Inhalation Toxicity of Aniline in Rats: Analysis of Time-Dependence and Concentration-Dependence of Hematotoxic and Splenic Effects Toxicol. Sci., September 1, 2004; 81(1): 198 - 215. [Abstract] [Full Text] [PDF] H. Munakata, J.-Y. Sun, K. Yoshida, T. Nakatani, E. Honda, S. Hayakawa, K. Furuyama, and N. Hayashi Role of the Heme Regulatory Motif in the Heme-Mediated Inhibition of Mitochondrial Import of 5-Aminolevulinate Synthase J. Biochem., August 1, 2004; 136(2): 233 - 238. [Abstract] [Full Text] [PDF] R. J. Crisp, A. Pollington, C. Galea, S. Jaron, Y. Yamaguchi-Iwai, and J. Kaplan Inhibition of Heme Biosynthesis Prevents Transcription of Iron Uptake Genes in Yeast J. Biol. Chem., November 14, 2003; 278(46): 45499 - 45506. [Abstract] [Full Text] [PDF] F. K. Johnson and R. A. Johnson Carbon monoxide promotes endothelium-dependent constriction of isolated gracilis muscle arterioles Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2003; 285(3): R536 - R541. [Abstract] [Full Text] [PDF] S. Park, O. Gakh, H. A. O'Neill, A. Mangravita, H. Nichol, G. C. Ferreira, and G. Isaya Yeast Frataxin Sequentially Chaperones and Stores Iron by Coupling Protein Assembly with Iron Oxidation J. Biol. Chem., August 15, 2003; 278(33): 31340 - 31351. [Abstract] [Full Text] [PDF] M. L. Klebig, M. D. Wall, M. D. Potter, E. L. Rowe, D. A. Carpenter, and E. M. Rinchik Mutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice PNAS, July 8, 2003; 100(14): 8360 - 8365. [Abstract] [Full Text] [PDF] F. A. Lara, U. Lins, G. Paiva-Silva, I. C. Almeida, C. M. Braga, F. C. Miguens, P. L. Oliveira, and M. Dansa-Petretski A new intracellular pathway of haem detoxification in the midgut of the cattle tick Boophilus microplus: aggregation inside a specialized organelle, the hemosome J. Exp. Biol., May 15, 2003; 206(10): 1707 - 1715. [Abstract] [Full Text] [PDF] E. Lesuisse, R. Santos, B. F. Matzanke, S. A. B. Knight, J.-M. Camadro, and A. Dancis Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1) Hum. Mol. Genet., April 15, 2003; 12(8): 879 - 889. [Abstract] [Full Text] [PDF] K. Hafid-Medheb, Y. Augery-Bourget, M.-N. Minatchy, N. Hanania, and J. Robert-Lezenes Bcl-XL is required for heme synthesis during the chemical induction of erythroid differentiation of murine erythroleukemia cells independently of its antiapoptotic function Blood, April 1, 2003; 101(7): 2575 - 2583. [Abstract] [Full Text] [PDF] M. Cazzola, R. Invernizzi, G. Bergamaschi, S. Levi, B. Corsi, E. Travaglino, V. Rolandi, G. Biasiotto, J. Drysdale, and P. Arosio Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia Blood, March 1, 2003; 101(5): 1996 - 2000. [Abstract] [Full Text] [PDF] H. Harigae, O. Nakajima, N. Suwabe, H. Yokoyama, K. Furuyama, T. Sasaki, M. Kaku, M. Yamamoto, and S. Sassa Aberrant iron accumulation and oxidized status of erythroid-specific delta -aminolevulinate synthase (ALAS2)-deficient definitive erythroblasts Blood, February 1, 2003; 101(3): 1188 - 1193. [Abstract] [Full Text] [PDF] Y. N. J. Strube, J. L. Beard, and A. C. Ross Iron Deficiency and Marginal Vitamin A Deficiency Affect Growth, Hematological Indices and the Regulation of Iron Metabolism Genes in Rats J. Nutr., December 1, 2002; 132(12): 3607 - 3615. [Abstract] [Full Text] [PDF] L. Lobmayr, T. Sauer, I. Killisch, M. Schranzhofer, R. B. Wilson, P. Ponka, H. Beug, and E. W. Mullner Transferrin receptor hyperexpression in primary erythroblasts is lost on transformation by avian erythroblastosis virus Blood, June 17, 2002; 100(1): 289 - 298. [Abstract] [Full Text] [PDF] B. Corsi, A. Cozzi, P. Arosio, J. Drysdale, P. Santambrogio, A. Campanella, G. Biasiotto, A. Albertini, and S. Levi Human Mitochondrial Ferritin Expressed in HeLa Cells Incorporates Iron and Affects Cellular Iron Metabolism J. Biol. Chem., June 14, 2002; 277(25): 22430 - 22437. [Abstract] [Full Text] [PDF] F. M. Torti and S. V. Torti Regulation of ferritin genes and protein Blood, May 15, 2002; 99(10): 3505 - 3516. [Full Text] [PDF] E. M. Becker, J. M. Greer, P. Ponka, and D. R. Richardson Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization Blood, May 15, 2002; 99(10): 3813 - 3822. [Abstract] [Full Text] [PDF] F. Canonne-Hergaux, A.-S. Zhang, P. Ponka, and P. Gros Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice Blood, December 15, 2001; 98(13): 3823 - 3830. [Abstract] [Full Text] [PDF] J. A. Roth, C. Horbinski, L. Feng, K. G. Dolan, D. Higgins, and M. D. Garrick Differential Localization of Divalent Metal Transporter 1 with and without Iron Response Element in Rat PC12 and Sympathetic Neuronal Cells J. Neurosci., October 15, 2000; 20(20): 7595 - 7601. [Abstract] [Full Text] [PDF] V. Dzikaite, A. Kanopka, J. H. Brock, A. Kazlauskas, and O. Melefors A novel endoproteolytic processing activity in mitochondria of erythroid cells and the role in heme synthesis Blood, July 15, 2000; 96(2): 740 - 746. [Abstract] [Full Text] [PDF] J. Balla, G. Balla, V. Jeney, G. Kakuk, H. S. Jacob, and G. M. Vercellotti Ferriporphyrins and endothelium: a 2-edged sword---promotion of oxidation and induction of cytoprotectants Blood, June 1, 2000; 95(11): 3442 - 3450. [Abstract] [Full Text] [PDF] P. Zhang, V. Sawicki, A. Lewis, L. Hanson, J. Monks, and M. C Neville The effect of serum iron concentration on iron secretion into mouse milk J. Physiol., February 1, 2000; 522(3): 479 - 491. [Abstract] [Full Text] [PDF] I. R. de Mena, M. A. Fernandez-Moreno, B. Bornstein, L. S. Kaguni, and R. Garesse Structure and Regulated Expression of the delta -Aminolevulinate Synthase Gene from Drosophila melanogaster J. Biol. Chem., December 24, 1999; 274(52): 37321 - 37328. [Abstract] [Full Text] [PDF] W. Mikulits, M. Schranzhofer, A. Bauer, H. Dolznig, L. Lobmayr, A. A. Infante, H. Beug, and E. W. Mullner Impaired Ferritin mRNA Translation in Primary Erythroid Progenitors: Shift to Iron-Dependent Regulation by the v-ErbA Oncoprotein Blood, December 15, 1999; 94(12): 4321 - 4332. [Abstract] [Full Text] [PDF] A. M. Konijn, H. Glickstein, B. Vaisman, E. G. Meyron-Holtz, I. N. Slotki, and Z. I. Cabantchik The Cellular Labile Iron Pool and Intracellular Ferritin in K562 Cells Blood, September 15, 1999; 94(6): 2128 - 2134. [Abstract] [Full Text] [PDF] L. Tacchini, L. Bianchi, A. Bernelli-Zazzera, and G. Cairo Transferrin Receptor Induction by Hypoxia. HIF-1-MEDIATED TRANSCRIPTIONAL ACTIVATION AND CELL-SPECIFIC POST-TRANSCRIPTIONAL REGULATION J. Biol. Chem., August 20, 1999; 274(34): 24142 - 24146. [Abstract] [Full Text] [PDF] C. N. Lok and P. Ponka Identification of a Hypoxia Response Element in the Transferrin Receptor Gene J. Biol. Chem., August 20, 1999; 274(34): 24147 - 24152. [Abstract] [Full Text] [PDF] L. Fayadat, P. Niccoli-Sire, J. Lanet, and J.-L. Franc Role of Heme in Intracellular Trafficking of Thyroperoxidase and Involvement of H2O2 Generated at the Apical Surface of Thyroid Cells in Autocatalytic Covalent Heme Binding J. Biol. Chem., April 9, 1999; 274(15): 10533 - 10538. [Abstract] [Full Text] [PDF] D. C. Radisky, M. C. Babcock, and J. Kaplan The Yeast Frataxin Homologue Mediates Mitochondrial Iron Efflux. EVIDENCE FOR A MITOCHONDRIAL IRON CYCLE J. Biol. Chem., February 19, 1999; 274(8): 4497 - 4499. [Abstract] [Full Text] [PDF] D Pountney, G Trugnan, M Bourgeois, and C Beaumont The identification of ferritin in the nucleus of K562 cells, and investigation of a possible role in the transcriptional regulation of adult beta-globin gene expression J. Cell Sci., January 3, 1999; 112(6): 825 - 831. [Abstract] [PDF] S. Taketani, Y. Adachi, H. Kohno, S. Ikehara, R. Tokunaga, and T. Ishii Molecular Characterization of a Newly Identified Heme-binding Protein Induced during Differentiation of urine Erythroleukemia Cells J. Biol. Chem., November 20, 1998; 273(47): 31388 - 31394. [Abstract] [Full Text] [PDF] S. Takahashi, S. Taketani, J.-e. Akasaka, A. Kobayashi, N. Hayashi, M. Yamamoto, and T. Nagai Differential Regulation of Coproporphyrinogen Oxidase Gene Between Erythroid and Nonerythroid Cells Blood, November 1, 1998; 92(9): 3436 - 3444. [Abstract] [Full Text] [PDF] A. Spadaccini, P. A. Tilbrook, M. K. Sarna, M. Crossley, J. J. Bieker, and S. P. Klinken Transcription Factor Erythroid Kruppel-like Factor (ELKF) Is Essential for the Erythropoietin-induced Hemoglobin Production but Not for Proliferation, Viability, or Morphological Maturation J. Biol. Chem., September 11, 1998; 273(37): 23793 - 23798. [Abstract] [Full Text] [PDF] M. Juckett, Y. Zheng, H. Yuan, T. Pastor, W. Antholine, M. Weber, and G. Vercellotti Heme and the Endothelium. EFFECTS OF NITRIC OXIDE ON CATALYTIC IRON AND HEME DEGRADATION BY HEME OXYGENASE J. Biol. Chem., September 4, 1998; 273(36): 23388 - 23397. [Abstract] [Full Text] [PDF] H. Tsukahara, C. Hori, M. Hiraoka, M. Mayumi, T. Okada, and F. Gejyo Nitric Oxide Modulation of Erythropoiesis in Rats Blood, July 1, 1997; 90(1): 473 - 474. [Full Text] [PDF] S. Levi, B. Corsi, M. Bosisio, R. Invernizzi, A. Volz, D. Sanford, P. Arosio, and J. Drysdale A Human Mitochondrial Ferritin Encoded by an Intronless Gene J. Biol. Chem., June 29, 2001; 276(27): 24437 - 24440. [Abstract] [Full Text] [PDF] C. N. Lok and P. Ponka Identification of an Erythroid Active Element in the Transferrin Receptor Gene J. Biol. Chem., July 28, 2000; 275(31): 24185 - 24190. [Abstract] [Full Text] [PDF] M. H. F. Sorgine, C. Logullo, R. B. Zingali, G. O. Paiva-Silva, L. Juliano, and P. L. Oliveira A Heme-binding Aspartic Proteinase from the Eggs of the Hard Tick Boophilus microplus J. Biol. Chem., September 8, 2000; 275(37): 28659 - 28665. [Abstract] [Full Text] [PDF] C. M. Maya-Monteiro, S. Daffre, C. Logullo, F. A. Lara, E. W. Alves, M. L. Capurro, R. Zingali, I. C. Almeida, and P. L. Oliveira HeLp, a Heme Lipoprotein from the Hemolymph of the Cattle Tick, Boophilus microplus J. Biol. Chem., November 17, 2000; 275(47): 36584 - 36589. [Abstract] [Full Text] [PDF] A. Caltagirone, G. Weiss, and K. Pantopoulos Modulation of Cellular Iron Metabolism by Hydrogen Peroxide. EFFECTS OF H2O2 ON THE EXPRESSION AND FUNCTION OF IRON-RESPONSIVE ELEMENT-CONTAINING mRNAs IN B6 FIBROBLASTS J. Biol. Chem., June 8, 2001; 276(23): 19738 - 19745. [Abstract] [Full Text] [PDF]

	Copyright © 1997 by American Society of Hematology         Online ISSN: 1528-0020