Supplemental materials for: Schwering et al, Vol 101, Issue 4, 1505-1512.

Supplemental Tables:

Table 1. The 286 genes down-regulated in Hodgkin cell line L1236 (Excel file, 39 KB): Tag numbers for centroblasts (CB) and L1236 are normalized to 30,000 tags. The tag numbers are rounded up or down. Differential expression was quantified by generating the quotient of tag numbers of both profiles (for 0 set 1), which is given as the factor of down- or up-regulation. All genes showing a decrease or increase of 5.0 or higher in expression were included in the analysis. The tag-to-gene assignment can be performed on the website http://www.ncbi.nlm.nih.gov/SAGE/.

Table 2: The 176 genes up-regulated in Hodgkin cell line L1236 (Excel file, 29 KB): Tag numbers for centroblasts (CB) and L1236 are normalized to 30,000 tags. The tag numbers are rounded up or down. The differential expression was quantified by generating the quotient of tag numbers of both profiles (for 0 set 1), which is given as the factor of down- or up-regulation. All genes showing a decrease or increase of 5.0 or higher in expression were included in the analysis. The tag-to-gene assignment can be performed on the website http://www.ncbi.nlm.nih.gov/SAGE/.

Table 3: Identification of genes differentially expressed in Hodgkin cell lines and normal B-cell subsets (Excel file, 523 KB): Columns show the z score, the GenBank accession numbers of the genes identified with a short description, the Affymetrix entry numbers, and the normalized primary data obtained from 4 Hodgkin lymphoma cell lines (L428, L1236, KMH2, HDLM2) and 5 samples each of centroblasts (CB), centrocytes (CC), naive B cells (N), and memory B cells (M). Genes are ranked as described in "Materials and Methods" according to the z score. In addition to the normalized primary data, the Affmetrix "present/absent" score for each value is given (P indicates present; M, marginal; and A, absent).





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