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Blood, 1 January 2004, Vol. 103, No. 1, pp. 11. This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Blood Work Social Bookmarking                   What's this?  Previous Article  |  Table of Contents  |  Next Article  BLOOD WORK Hereditary spherocytosis This smear is from a patient with hereditary spherocytosis. Note the dense microspherocytes with absent central pallor. Because of an inherited abnormality in structural red cell membrane proteins, the red cell sheds microparticles such that the membrane loses surface area. The result is that the red cell can no longer maintain its biconcave disc shape and becomes more spherocytic, a shape that jeopardizes passage of affected RBCs from the splenic cords into the sinuses. Stanley Schrier, Stanford University School of Medicine   [View Larger Version of this Image (133K GIF file)]   The above image was first published in the ASH IMAGE BANK, a reference and teaching tool that is continually updated with new atlas images and images of case studies. For more information or to contribute to the Image Bank, visit ashimagebank.hematologylibrary.org. CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this? This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Rights and Permissions Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Blood Work Social Bookmarking                   What's this?

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